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Structure-driven pharmacology of transient receptor potential channel vanilloid 1
(2016)
The transient receptor potential vanilloid 1 (TRPV1) ion channel is a polymodal receptor that mediates the flux of cations across the membrane in response to several stimuli, including heat, voltage, and ligands. The best ...
Structure-driven pharmacology of transient receptor potential channel vanilloid 1
(2016)
The transient receptor potential vanilloid 1 (TRPV1) ion channel is a polymodal receptor that mediates the flux of cations across the membrane in response to several stimuli, including heat, voltage, and ligands. The best ...
Ontogenetic expression of the vanilloid receptors TRPV1 and TRPV2 in the rat retina
(PERGAMON-ELSEVIER SCIENCE LTD, 2009)
The present study aimed to analyze the gene and protein expression and the pattern of distribution of the vanilloid receptors TRPV1 and TRPV2 in the developing rat retina. During the early phases of development, TRPV1 was ...
Opposing Roles for Cannabinoid Receptor Type-1 (CB1) and Transient Receptor Potential Vanilloid Type-1 Channel (TRPV1) on the Modulation of Panic-Like Responses in Rats
(NATURE PUBLISHING GROUPLONDON, 2013-08-02)
The midbrain dorsal periaqueductal gray (dPAG) has an important role in orchestrating anxiety-and panic-related responses. Given the cellular and behavioral evidence suggesting opposite functions for cannabinoid type 1 ...
Novel TRPV1 Channel Agonists With Faster and More Potent Analgesic Properties Than Capsaicin
(Frontiers Media S.A, 2020-07)
The transient receptor potential vanilloid 1 (TRPV1) ion channel is a member of the family of Transient Receptor Potential (TRP) channels that acts as a molecular detector of noxious signals in primary sensory neurons. ...
Design and synthesis of conformationally restricted capsaicin analogues based in the 1, 3, 4-thiadiazole heterocycle reveal a novel family of transient receptor potential vanilloid 1 (trpv1) antagonists
(ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2013)