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The TGF-β Pathway as an Emerging Target for Chagas Disease Therapy
(American Society for Clinical Pharmacology and Therapeutics, 2017)
Differential uPA expression by TGF-β1 in gingival fibroblasts
(2006)
Transforming Growth Factor-β1 (TGF-β1) plays a key role in connective tissue remodeling and inflammation. Under pathological conditions, like periodontal disease, fibroblasts may display an altered response to this growth ...
SMAD3 is essential for transforming growth factor-β1-induced urokinase type plasminogen activator expression and migration in transformed keratinocytes
(2012)
Transforming growth factor-β1 (TGF-β1) stimulates the extracellular matrix degrading proteases expression and cell migration in order to enhance cancer cells malignancy. In the present study, we analysed the role of ...
Plasma levels of TGF-β1 in homeostasis of the inflammation in sickle cell disease
(2016-04-01)
Sickle cell disease (SCD) represents a chronic inflammatory condition with complications triggered by the polymerization of hemoglobin S (Hb S), resulting in a series of cellular interactions mediated by inflammatory ...
Glial-derived transforming growth factor β1 (TGF-β1): A key factor in multiple sclerosis neuroinflammation
(Wolters Kluwer Medknow Publications, 2020-09-22)
Association of increased levels of TGF-β1 and p14ARF in prostate carcinoma cell lines overexpressing Egr-1
(Spandidos Publications, 2014)
The present study examined the effect of the overexpression of early growth response gene (Egr-1) on transforming growth factor β-1 (TGF-β1) and p14ARFlevels, in PC-3 and LNCaP prostate carcinoma cell lines. Amplification ...
TGF-β receptor type II costameric localization in cardiomyocytes and host cell TGF-β response is disrupted by Trypanosoma cruzi infection
(Cambridge University Press, 2016)
Effect of exogenous transforming growth factor β1 (TGF-β1) on early bovine embryo development
(Cambridge University Press, 2018-06)
During preimplantation development, embryos are exposed and have the capacity to respond to different growth factors present in the maternal environment. Among these factors, transforming growth factor β1 (TGF-β1) is a ...
Effect of transforming growth factor beta (TGF-β) receptor I kinase inhibitor on prostate cancer bone growth
(Elsevier Science Inc, 2012-03)
Transforming growth factor beta 1 (TGF-β1) has been implicated in the pathogenesis of prostate cancer (PCa) bone metastasis. In this study, we tested the antitumor efficacy of a selective TGF-β receptor I kinase inhibitor, ...