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The Importance of Nanocarrier Design and Composition for an Efficient Nanoparticle-Mediated Transdermal Vaccination
(MDPI, 2021)
The World Health Organization estimates that the pandemic caused by the SARS-CoV-2 virus claimed more than 3 million lives in 2020 alone. This situation has highlighted the importance of vaccination programs and the urgency ...
Nanogeles bifuncionales y su aplicación en vacunación transdermal
(2019-02-22)
In this thesis, a needle-free, easy to use and non-invasive vaccination system was developed. The system consist of nanogels that have two functions (that is why we call them bifunctional): they are sensitive to temperature ...
Effect of Delivery Platforms Structure on the Epidermal Antigen Transport for Topical Vaccination
(American Chemical Society, 2018-12)
Transdermal immunization is highly attractive because of the skin's accessibility and unique immunological characteristics. However, it remains a relatively unexplored route of administration because of the great difficulty ...
Nanocarriers for Skin Applications: Where Do We Stand?
(Wiley VCH Verlag, 2021-09)
Skin penetration of active molecules for treatment of diverse diseases is a major field of research owing to the advantages associated with the skin like easy accessibility, reduced systemic-derived side effects, and ...
Análisis de nuevos vehículos y adyuvantes para inmunización con antígenos de Staphylococcus aureus utilizando diferentes modelos experimentales
(2020-12-01)
Se estima que la bacteria Staphylococcus aureus, es la responsable del 20-25% de las infecciones intra-hospitalarias. Por otra parte, la mastitis bovina es un claro ejemplo de los efectos de este patógeno en el ámbito ...
Dendrimers as potential platform in nanotechnology-based drug delivery systems
(2012)
The dendrimers of poly (amidoamine) (PAMAM) are nanoparticles which have proven succeed in transporting drugs due to high solubility, low toxicity and ability to control drugs release. Studies have explored the biological ...
Nuevas plataformas poliméricas para su uso en biotecnología
Se considera el desarrollo de nuevas plataformas poliméricas diseñadas con características especiales y dirigidas a diferentes aplicaciones biotecnológicas: i) partículas coloreadas funcionalizadas y sensibilizadas con ...
Estudio del Transporte de Péptidos a Través de Membranas con Permeabilidad Selectiva
(Escuela de químicaUniversidad Nacional de Colombia - Sede Medellín, 2019)
En este trabajo se estudió el transporte de tres péptidos a través de una membrana sintética tipo piel (Strat-M® SKBM02560). Los péptidos utilizados en este estudio (DM 1.14, DM1.16 y DM 1.18) son modificaciones de dos ...
Patogênese e terapia experimental da infecção pelo alfaherpesvírus bovino 2
(Universidade Federal de Santa MariaBrasilMedicina VeterináriaUFSMPrograma de Pós-Graduação em Medicina VeterináriaCentro de Ciências Rurais, 2020-08-25)
Bovine alphaherpesvirus 2 (BoHV-2) - the agent of bovine herpetic mamillitis (BHM) – is related to Human alphaherpesviruses 1 and 2 (HHV-1, HHV-2) and has been proposed as a model for vaccine and drug testing. In addition, ...