The vesicular acetylcholine transporter (VAChT) is the protein responsible for packaging cytoplasmic acetylcholine (ACh) into the synaptic vesicle of cholinergic neurons. The cytosolic C-terminal region of VAChT is important ...

O colesterol é um componente importante da membrana plasmática da célula. Devido à sua composição química (longa cadeia hidrofóbica rígida e um pequeno grupo hidroxila polar), ele se encaixa a maior parte de sua estrutura ...

Eosinophils are multifunctional cells from the immune system with activities associated with the secretion of numerous products stored in their cytoplasmic granules. One of the main mechanisms by which the eosinophil ...

Since the byosynthesis description of the (HS) heparan sulfate, it has been assumed that the modifications found in these polysaccharides - sulfation and epimerization - occur through a hierarchical sequence of enzymatic ...

Eosinophils are able to release numerous mediators that are pre-synthesized and stored within their cytoplasmic specific (secretory) granules. Secretion can occur by: (i) piecemeal degranulation (PMD), characterized by ...

O tráfego vesicular mediado por clatrina, mecanismo pelo qual proteínas e lipídeos são transportados entre organelas envolvidas por membrana, é responsável por uma grande proporção de interiorização de membrana plasmática ...