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Vitamin D decreases cell death and inflammation in human umbilical vein endothelial cells and placental explants from pregnant women with preeclampsia cultured with TNF-α
(2021-01-01)
This study evaluated the impact of vitamin D on Human Umbilical Vein Endothelial Cells (HUVEC) and inflammation in placental explants from women with preeclampsia (PE). HUVEC and explants from 10 late-onset PE (LOPE), 10 ...
TNF-α induces vascular insulin resistance via positive modulation of PTEN and decreased Akt/eNOS/NO signaling in high fat diet-fed mice
(BioMed Central, 2016)
Abstract
Background
High fat diet (HFD) induces insulin resistance in various tissues, including the vasculature. HFD also increases plasma levels of TNF-α, a cytokine that ...
Effect of TNF-α on molecules related to the insulin action in endometrial cells exposed to hyperandrogenic and hyperinsulinic conditions characteristics of polycystic ovary syndrome
(SAGE Publications Inc., 2018)
© The Author(s) 2017. Polycystic ovary syndrome (PCOS) affects not only ovarian functions but is also able to affect endometrium metabolism. Around 80% of women with PCOS are obese. High tumor necrosis factor (TNF)-α ...
Cytokine TNF‑α and its receptors TNFRI and TNFRII play a key role in the in vitro proliferative response of BLV infected animals
(Springer, 2021-08)
Bovine leukemia virus (BLV) main host cells are B lymphocytes. Infected animals can be classified into high or low proviral load (HPL or LPL respectively), regarding the number of proviral copies infected lymphocytes they ...
TNF-α and IL-6 immunohistochemistry in rat renal tissue experimentaly infected with Leptospira interrogans serovar Canicola
(Centro de Estudos de Venenos e Animais Peçonhentos - CEVAP, Universidade Estadual Paulista - UNESP, 2008-01-01)
Leptospirosis is a public health problem worldwide and its etiology remains unclear. Its pathogenesis involves a complex interaction between host and infecting microorganism. The inflammatory reaction that controls the ...
TNF-alpha affects signature cytokines of th1 and th17 t cell subsets through differential actions on TNFR1 and TNFR2
(MDPI, 2022)
Tumor necrosis factor (TNF)- is a pleiotropic cytokine implicated in the etiology of
several autoimmune diseases, including rheumatoid arthritis (RA). TNF- regulates diverse effector
functions through the activation ...
Effect of Anti-TNF-α on the Development of Offspring and Pregnancy Loss During Pregnancy in Rats
(Universidade Federal do Rio Grande do Sul, 2016)