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Trypanothione reductase inhibitors: Overview of the action of thioridazine in different stages of Chagas disease

Lo Presti, Maria Silvina; Bazán, Paola Carolina; Strauss, Mariana; Báez, Alejandra L.; Rivarola, Héctor Walter; Pagliani Oliva, Patricia A. (Elsevier Science, 2015-05)

Thioridazine (TDZ) is a phenothiazine that has been shown to be one of the most potent phenothiazines to inhibit trypanothione reductase irreversibly. Trypanothione reductase is an essential enzyme for the survival of ...