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Signaling triggered by Thy-1 interaction with β3 integrin on astrocytes is an essential step towards unraveling neuronal Thy-1 function
(2002)
Thy-1 is an abundant neuronal glycoprotein in mammals. Despite such prevalence, Thy-1 function remains largely obscure in the absence of a defined ligand. Recently described evidence that Thy-1 interacts with β3 integrin ...
Signaling triggered by Thy-1 interaction with ß3 integrin on astrocytes is an essential step towards unraveling neuronal Thy-1 function
(Sociedad de Biología de Chile, 2002)
Thy-1/CD90 a Bidirectional and Lateral Signaling Scaffold
(2019)
Thy-1/CD90 is a glycoprotein attached to the outer face of the plasma membrane with various functions, which depend on the context of specific physiological or pathological conditions. Many of these reported functions for ...
Astrocyte-to-neuron communication through integrin-engaged Thy-1/CBP/Csk/Src complex triggers neurite retraction via the RhoA/ROCK pathway
(2017)
Two key proteins for cellular communication between astrocytes and neurons are amp integrin and the receptor Thy-1. Binding of these molecules in the same (cis) or on adjacent (trans) cellular membranes induces Thy-1 ...
Astrocyte-to-neuron communication through integrin-engaged Thy-1/CBP/Csk/Src complex triggers neurite retraction via the RhoA/ROCK pathway
(2017)
Two key proteins for cellular communication between astrocytes and neurons are amp integrin and the receptor Thy-1. Binding of these molecules in the same (cis) or on adjacent (trans) cellular membranes induces Thy-1 ...
Integrin-mediated transactivation of P2X7R via hemichannel-dependent ATP release stimulates astrocyte migration
(Elsevier, 2016)
Our previous reports indicate that ligand-induced alpha(v)beta(3) integrin and Syndecan-4 engagement increases focal adhesion formation and migration of astrocytes. Additionally, ligated integrins trigger ATP release through ...
Characterization of alpha X I-domain binding to Thy-1
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2005-06-03)
The β 2 integrins are found exclusively in leukocytes and they are composed of a common β chain, CD18, and one of four unique α chains, CD11a (α L subunit), CD11b (α M subunit), CD11c (α ...
THY-1 MODULATES NEUROLOGICAL CELL-CELL AND CELL-MATRIX INTERACTIONS THROUGH MULTIPLE MOLECULAR INTERACTIONS
(SPRINGER, 2014)
Thy-1, or CD90, is a glycosylphosphatidylinositol-linked cell surface glycoprotein expressed on multiple cell types, including neurons, thymocytes, fibroblasts, endothelial cells, mesangial cells, and some hematopoietic ...