Buscar

Mostrando ítems 1-10 de 110

DIFFERENT ABILITIES OF THROMBIN RECEPTOR ACTIVATING PEPTIDE AND THROMBIN TO INDUCE PLATELET CALCIUM RISE AND FULL RELEASE REACTION

LASNE, D; DONATO, J; FALET, H; RENDU, F (F K Schattauer Verlag GmbhStuttgartAlemanha, 1995)

Effect of a thrombin receptor (protease-activated receptor 1, PAR-1) gene polymorphism in chronic hepatitis C liver fibrosis

MARTINELLI, Ana; KNAPP, Susanne; ANSTEE, Quentin; WORKU, Mulugeta; TOMMASI, Anna; ZUCOLOTO, Sergio; GOLDIN, Robert; THURSZ, Mark (WILEY-BLACKWELL, 2008)

Background and Aim: Tissue injury leads to activation of coagulation and generation of thrombin. Inhibition of thrombin receptor protease-activated receptor 1 (PAR-1) has been shown to reduce liver fibrosis in animals. ...

PLASMA KALLIKREIN and THROMBIN ARE CLEARED THROUGH UNRELATED HEPATIC PATHWAYS

Loureirosilva, M. R.; Kouyoumdjian, M.; Borges, D. R. (Rapid Science Publishers, 1993-08-01)

Plasma kallikrein (PK) and thrombin (TH), serine proteinases formed from inactive precursors, participate in important body defence mechanisms. the isolated hepatocyte recognizes TH, and the liver clears PK by calcium-independent ...

Platelet protease-activated receptor 1 and membrane expression of P-selectin in pulmonary arterial hypertension

MAEDA, Nair Y.; CARVALHO, Joao H.; OTAKE, Andreia H.; MESQUITA, Sonia M. F.; BYDLOWSKI, Sergio P.; LOPES, Antonio Augusto (PERGAMON-ELSEVIER SCIENCE LTD, 2010)

Introduction: Pulmonary arterial hypertension (PAH) is frequently associated with thrombotic events, particularly involving the pulmonary microcirculation at sites of vascular injury. We therefore decided to analyse ...

Gyroxin increases blood-brain barrier permeability to evans blue dye in mice

ALVES da SILVA, J.A.; OLIVEIRA, K.C.; CAMILLO, M.A.P. (2011)

Crystal structure of Jararacussin-I: The highly negatively charged catalytic interface contributes to macromolecular selectivity in snake venom thrombin-like enzymes

Ullah, Anwar; Souza, Tatiana de Arruda Campos Brasil de; Zanphorlin, Leticia Maria; Mariutti, Ricardo B.; Santana, V. S.; Murakami, Mario Tyago; Arni, R. K. (2016)

NF-κB signaling pathway as target for antiplatelet activity

Rojas, Armando; Fuentes, Eduardo; Palomo, Iván (2017)

Platelet adhesion and intracellular calcium levels in antigen-challenged rats

Baldissera, L; Monteiro, PF; de Mello, GC; Morganti, RP; Antunes, E (Academic Press Ltd- Elsevier Science LtdLondonInglaterra, 2010)

Changes in amniotic fluid concentration of thrombinantithrombin III complexes in patients with preterm labor: Evidence of an increased thrombin generation

Erez, O.; Romer, R.; Vaisbuch, E.; Chaiworapongsa, T.; Kusanovic, J.P.; Mazaki-Tovi, S.; Gotsch, F.; Gómez Mora, Ricardo; Maymon, E.; Pacora, P.; Edwin, S.S.; Kim, C.J.; Than, N.G.; Mittal, P.; Yeo, L.; Dong, Z.; Yoon, B.H.; Hassan, S.S.; Mazor, M. (2009)

Objective.Preterm labor is associated with excessive maternal thrombin generation, as evidenced by increased circulatingthrombin–antithrombin (TAT) III complexes concentration. In addition to its hemostatic ...

ATP Antagonizes Thrombin-Induced Signal Transduction through 12(S)-HETE and cAMP

Burzaco, Jaione; Conde, Manuel; Parada, Luis Antonio; Zugaza, José L.; Dehaye, Jean-Paul; Marino, Aída (Public Library Science, 2013-06-24)

In this study we have investigated the role of extracellular ATP on thrombin induced-platelet aggregation (TIPA) in washed human platelets. ATP inhibited TIPA in a dose-dependent manner and this inhibition was abolished ...

1
2
3
4
. . .
11