Buscar
Mostrando ítems 1-10 de 24
Synthesis, structural characterization and pro-apoptotic activity of Indanone thiosemicarbazones and their platinum (II) and paladium (II) complexes: Potential role as selective antileukemic agents
(Wiley VCH Verlag, 2011)
In the search for alternative chemotherapeutic strategies against leukemia, various 1-indanone thiosemicarbazones, as well as eight novel platinum(II) and palladium(II) complexes, with the formula [MCl2(HL)] and ...
ß-Cyclodextrin hydrogels for the ocular release of antibacterial thiosemicarbazones
(Elsevier, 2013-04-02)
Two types of hydrophilic networks with conjugated beta cyclodextrin (b-CD) were developed with the aim of engineering useful platforms for the localized release of an antimicrobial 5,6-dimethoxy-1-indanone N4-allyl ...
Materiales bioinorgánicos de paladio y cobre con compuestos orgánicos de actividad antitumoral
(Universidad de LimaPE, 2009)
En el presente trabajo se informa acerca de la preparación y caracterización de los compuestos orgánicos derivados del furaldehído tiosemicarbazona y sus respectivos complejos metálicos de paladio(II) y co bre(II). El ...
Thiosemicarbazone of lapachol acts on cell membrane in Paracoccidioides brasiliensis
(Oxford University Press, 2019)
Planejamento Estrutural, Síntese e Avaliação das Propriedades Tripanocidas de Novas ARIL-TIOSSEMICARBAZONAS
(Universidade Federal de PernambucoUFPEBrasilPrograma de Pos Graduacao em Ciencias Farmaceuticas, 2016)
N4-aryl substituted thiosemicarbazones derived from 1-indanones as potential anti-tumor agents for breast cancer treatment
(Wiley-liss, Div John Wiley & Sons Inc, 2018-06)
Breast cancer is the first cause of cancer death in women. Many patients are resistant to current therapies, and even those were sensitive at first may eventually become resistant later. Thiosemicarbazones (TSCs) are ...
Complexos metálicos de hidrazonas, tiossemicarbazonas e lapachol: atividade farmacológica e avaliação de relações estrutura-atividade
(Universidade Federal de Minas GeraisUFMG, 2012-02-10)
The present work comprises the synthesis and characterization of metal compounds with bioactive ligands and the study of their pharmacological profile. Anti-inflammatory, antimicrobial, antiparasitic and antitumor drug ...
Derivados nitrogenados planares: síntese, elucidação estrutural, docking e estudos de interação com o DNA e albumina do soro bovino
(Universidade Federal de PernambucoUFPEBrasilPrograma de Pos Graduacao em Ciencias Farmaceuticas, 2019)
Síntese e avaliação da atividade citotóxica de novos derivados tiossemicarbazônicos isoxazolínicos aza-bicíclicos
(Universidade Federal de PernambucoUFPEBrasilPrograma de Pos Graduacao em Ciencias Farmaceuticas, 2017)
Avaliação da potencial aplicação de derivados de 2-acetilpiridina N-4 fenil tiossemicarbazonas em terapia e diagnóstico oncológico
(Universidade Federal de Minas GeraisUFMG, 2013-03-25)
Despite the wide range of antineoplastic agents available, resistance of some types of cancer and toxicity to normal cells have been identified as the main causes of treatment failure and death. The lack of early and precise ...