Buscar

Mostrando ítems 1-10 de 28

Thiopurines: Use them or lose them? International survey on current and future use of thiopurines in inflammatory bowel disease

Tondela-Viseu Hospital Centre; Universita Cattolica; Goethe-University; Oslo University Hospital; Hospital Clínico Universitario de Santiago de Compostela; University Hospital; Universidade Estadual Paulista (UNESP); Catholic University of Paraná (PUCPR); University of Lorraine; University of Porto; São João University Hospital; Centre for Drug Discovery and Innovative Medicines (2021-01-01)

Background and aims: The role of thiopurines in therapeutic algorithms of Crohn's disease (CD) and Ulcerative colitis (UC) is being questioned. This work aimed to investigate current practice and future perspectives of ...

Impact of Anti-TNF and Thiopurines medications on the development of COVID-19 in patients with inflammatory bowel disease: A Nationwide VA cohort study

Patel, Dhruvan; Xie, Dawei; Lewis, James

The recent outbreak of novel Coronavirus disease 2019 (COVID-19) has become a pandemic and is threatening global health.1 The highest number of COVID-19 confirmed cases were reported in the United States, with 1.47 ...

6-methylmercaptopurine riboside, a thiopurine nucleoside with antiviral activity against canine distemper virus in vitro

Universidade Federal de Viçosa (UFV); Universidade Federal de Pernambuco (UFPE); Universidade Estadual Paulista (Unesp) (Biomed Central Ltd, 2017-06-26)

Background: Canine distemper (CD) is a widespread infectious disease that can severely impact a variety of species in the order Carnivora, as well as non-carnivore species such as non-human primates. Despite large-scale ...

Phenotype and genotype of thiopurine methyltransferase in chilean individuals

Autor desconocido (SOCIEDAD MEDICA DE SANTIAGO, 2012)

Cost-utility Analysis : Thiopurines Plus Endoscopy-guided Biological Step-up Therapy is the Optimal Management of Postoperative Crohn's Disease

Candia, Roberto; Naimark, D.; Sander, B.; Nguyen, G. (2017)

Phenotype and genotype of thiopurine methyltransferase in Chilean individuals

Jorquera, Andres; Solari, Sandra; Vollrath, Valeska; Guerra, Irene; Chianale, Jose; Cofre, Colomba; Kalergis, Alexis; Ibanez, Patricio; Bueno, Susan; Alvarez Lobos, Manuel (SOC MEDICA SANTIAGO, 2012)

Background: Thiopurines (azathioprine and 6-mercaptopurine) are highly effective medications but with potential adverse effects. Thiopurine methyltransferase (TMPT) is the key enzyme in their pharmacokinetics and is ...

Split-dose administration of thiopurine drugs: a novel and effective strategy for managing preferential 6-MMP metabolism

Shih, D. Q.; Nguyen, M.; Zheng, L.; Ibanez, P.; Mei, L.; Kwan, L. Y.; Bradford, K.; Ting, C.; Targan, S. R.; Vasiliauskas, E. A. (WILEY-BLACKWELL, 2012)

Background Mercaptopurine and azathioprine (AZA) are efficacious in treating IBD. 6-tioguanine (6-TGN) levels correlate with therapeutic efficacy, whereas high 6-methylmercaptopurine (6-MMP) levels are associated with ...

Analysis of Thiopurine S-Methyltransferase Deficient Alleles in Acute Lymphoblastic Leukemia Patients in Mexican Patients

DORIS DEL CARMEN PINTO ESCALANTE (info)

The thiopurine nucleoside analogue 6-methylmercaptopurine riboside (6MMPr) effectively blocks zika virus replication

Carvalho, Otavio Valério de; Félix, Daniele Mendes; Mendonça, Leila Rodrigues de; Araújo, Catarina Maria Cataldi Sabino de; Franca, Rafael Freitas de Oliveira; Cordeiro, Marli Tenório; Júnior, Abelardo Silva; Pena, Lindomar José (Elsevier, 2017)

Rectal diffuse large B cell lymphoma appearing after immunosuppression for ulcerative colitis. Report of one case

Quera, Rodrigo; Flores, Lilian; Simian, Daniela; Kronberg, Udo; Teresa Vial, Maria; Ladron De Guevara, David; Jose Garcia Rodriguez, Maria (SOC MEDICA SANTIAGO, 2017)

Primary colorectal lymphoma is a rare form of presentation of gastrointestinal tract lymphomas. Inflammatory bowel disease and its treatment are risk factors for its development. We report a 47-year-old male patient with ...