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Human ADMC-Derived Adipocyte Thermogenic Capacity Is Regulated by IL-4 Receptor
(Stem Cells International, 2017-10-12)
Type two innate immune system is anti-inflammatory and may play an important role as the means whereby “browning” is induced in subcutaneous adipocytes. It was shown that IL-4 may influence the fate of adipose cell precursors ...
Multidimensional single-nuclei rna-seq reconstruction of adipose tissue reveals adipocyte plasticity underlying thermogenic response
(2021-11-01)
Adipose tissue has been classified based on its morphology and function as white, brown, or beige/brite. It plays an essential role as a regulator of systemic metabolism through paracrine and endocrine signals. Recently, ...
Nutraceutical Food: Composition, Biosynthesis, Therapeutic Properties, and Applications
(2018-03-09)
Diseases, such as cardiovascular system problems, diabetes, obesity, and cancer are frequent in last decades due to poor eating habits and sedentary lifestyle, mainly in industrialized countries where population consumes ...
Hypothalamic Actions of Tumor Necrosis Factor alpha Provide the Thermogenic Core for the Wastage Syndrome in Cachexia
(ENDOCRINE SOC, 2010)
TNF alpha is an important mediator of catabolism in cachexia. Most of its effects have been characterized in peripheral tissues, such as skeletal muscle and fat. However, by acting directly in the hypothalamus, TNF alpha ...
Modifications of Human Subcutaneous ADMSC after PPARγ Activation and Cold Exposition
(Stem Cells International, 2015-08-03)
Mesenchymal stem cells are a diverse population of cells with a wide range of potential therapeutic applications. In particular, cells from adipose tissue have the distinction of being easily accessible and contain a lot ...
Uso off-label da semaglutida em adultos com obesidade: uma visão integrativa
(Universidade Federal de São Paulo, 2023-06-27)
A obesidade é considerada uma doença crônica, em crescimento global e que está
relacionada ao desenvolvimento de outras doenças que são enquadradas na
chamada Síndrome Metabólica. Com base na análise do nível e no ...
3,3',5-Triiodothyronine-induced hepatic respiration: Effects of desferrioxamine and allopurinol in the isolated perfused rat liver
(1993)
The effect of daily doses of 0.1 mg 3,3',5-triiodothyronine (T3) kg for three consecutive days on hepatic O2 uptake was studied in the isolated perfused rat liver, in the absence and presence of the antioxidants desferrioxamine ...
The Role of Physical Exercise to Improve the Browning of White Adipose Tissue via POMC Neurons
(Frontiers Media Sa, 2018-03-28)
Obesity is a public health issue that affects more than 600 million adults worldwide. The disease is characterized by fat accumulation, mainly in the abdominal area. The human body is mainly composed of two types of adipose ...
Avaliação do efeito do extrato aquoso de Ilex paraguariensis e cafeína sobre o metabolismo e a doença de Alzheimer em Caenorhabditis elegans
(Universidade Federal de Santa MariaBrasilBioquímicaUFSMPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica ToxicológicaCentro de Ciências Naturais e Exatas, 2020-03-25)
Ilex paraguariensis is a plant widely consumed in South America, used to prepare a tea-like beverage, called mate, rich in caffeine and polyphenols, with multiple biological activities including antioxidant, anti-obesity ...
Análise do perfil metabólico de camundongos tratados com crotamina por via oral
(Universidade Federal de São Paulo (UNIFESP), 2016-10-31)
A crotamina tem sido amplamente estudada nos últimos anos, e diversas propriedades e atividades biológicas já foram descritas, como por exemplo, sua capacidade de penetrar células com seletividade por células com alta taxa ...