Buscar
Mostrando ítems 1-10 de 181
A structural view of ligand-dependent activation in thermoTRP channels
(Frontiers Research Foundation, 2014)
Transient Receptor Potential (TRP) proteins are a large family of ion channels, grouped into seven sub-families. Although great advances have been made regarding the activation and modulation of TRP channel activity, ...
TRP channels regulation of Rho GTPases in brain context and diseases
(Frontiers Media, 2020)
Neurological and neuropsychiatric disorders are mediated by several pathophysiological mechanisms, including developmental and degenerative abnormalities caused primarily by disturbances in cell migration, structural ...
Unitary Recordings of TRP and TRPL Channels From Isolated Drosophila Retinal Photoreceptor Rhabdomeres: Activation by Light and Lipids
(AMER PHYSIOLOGICAL SOC, 2009-03-02)
Delgado R, Bacigalupo J. Unitary recordings of TRP and TRPL
channels from isolated Drosophila retinal photoreceptor rhabdomeres:
activation by light and lipids. J Neurophysiol 101: 2372–2379, 2009.
First published March ...
Coordinated gating of TRP-dependent channels in rhabdomeral membranes from Drosophila retinas
(Society for Neuroscience, 2000)
Using a newly developed dissociation procedure, we isolated the specialized rhabdomeral membranes from Drosophila retinal photoreceptors. From these membranes, we have recorded spontaneous active currents in excised patch, ...
TRP channels in sensory tansduction
(Springer, 2015)
Diacylglycerol Activates the Light-Dependent Channel TRP in the Photosensitive Microvilli of Drosophila melanogaster Photoreceptors
(Society for Neuroscience, 2014)
Drosophila light-dependent channels, TRP and TRPL, reside in the light-sensitive microvilli of the photoreceptor’s rhabdomere. Phospholipase
C mediates TRP/TRPL opening, but the gating process remains unknown. Controversial ...
Differential regulation of TRP channels in a rat model of neuropathic pain
(ELSEVIER SCIENCE BV, 2009)
Neuropathic pain is a chronic disease resulting from dysfunction of the nervous system often due to peripheral nerve injury. Hypersensitivity to sensory Stimuli (mechanical, thermal or chemical) is a common source of pain ...
MUTAGENESIS AND TEMPERATURE-SENSITIVE LITTLE MACHINES
(INTECH, 2012)
In mammals a class of ion channels able to sense a wide range of temperatures (0-60 °C) has evolved. These molecular thermodynamic machines called thermo Transient Receptor Potential (thermoTRP) are spread through the ...