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Modulation of thyroid hormone receptors, TR alpha and TR beta, by using different doses of triiodothyronine (T3) at different times
(Sbem-soc Brasil Endocrinologia & Metabologia, 2013-07-01)
Objective: To examine the effect of different doses of triiodothyronine (T3) on mRNA levels of thyroid hormone receptors, TR alpha and TR beta, at different times. Materials and methods: 3T3-L1 adipocytes were incubated ...
Modulation of thyroid hormone receptors, TR alpha and TR beta, by using different doses of triiodothyronine (T3) at different times
(Sbem-soc Brasil Endocrinologia & Metabologia, 2014)
Ligand induced interaction of thyroid hormone receptor beta with its coregulators
(PERGAMON-ELSEVIER SCIENCE LTD, 2008)
Thyroid hormones exert most of their physiological effects through two thyroid hormone receptor (TR) subtypes, TR alpha and TR beta, which associate with many transcriptional coregulators to mediate activation or repression ...
Modulation of thyroid hormone receptors, TR alpha and TR beta, by using different doses of triiodothyronine (T3) at different timesModulação dos receptores de hormônio tireoidiano, TRα e TRβ, utilizando diferentes doses de triiodotironina (T3) em diferentes tempos
(Sbem-soc Brasil Endocrinologia & Metabologia, 2014)
Gaining ligand selectivity in thyroid hormone receptors via entropy
(NATL ACAD SCIENCES, 2009)
Nuclear receptors are important targets for pharmaceuticals, but similarities between family members cause difficulties in obtaining highly selective compounds. Synthetic ligands that are selective for thyroid hormone (TH) ...
The Thyroid Hormone Receptor (TR) beta-Selective Agonist GC-1 Inhibits Proliferation But Induces Differentiation and TR beta mRNA Expression in Mouse and Rat Osteoblast-Like Cells
(SPRINGER, 2009)
Previous studies showed anabolic effects of GC-1, a triiodothyronine (T3) analogue that is selective for both binding and activation functions of thyroid hormone receptor (TR) beta 1 over TR alpha 1, on bone tissue in vivo. ...
Camperdown hemoglobin associated with beta degrees thalassemia in a Brazilian child
(Soc Brasil GeneticaRibeirao PretBrasil, 2005)
Identification of potential trypanothione reductase inhibitors among commercially available beta-carboline derivatives using chemical space, lead-like and drug-like filters, pharmacophore models and molecular docking
(2017)
American trypanosomiasis or Chagas disease caused by the protozoan Trypanosoma cruzi (T. cruzi) is an important endemic trypanosomiasis in Central and South America. This disease was considered to be a priority in the ...
Recognition by the Thyroid Hormone Receptor of Canonical DNA Response Elements
(AMER CHEMICAL SOC, 2010)
To shed more light on the molecular requirements for recognition of thyroid response elements (TRES) by thyroid receptors (TRs), we compared the specific aspects of DNA TRE recognition by different TR constructs. Using ...