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Candida albicans Tpk1p and Tpk2p isoforms differentially regulate pseudohyphal development, biofilm structure, cell aggregation and adhesins expression
(John Wiley & Sons Ltd, 2011-04)
Candida albicans undergoes a reversible morphological transition from single yeast cells to pseudohyphal and hyphal filaments. In this organism, cAMP-dependent protein kinase (PKA), coded by two catalytic subunits (TPK1 ...
Catalytic isoforms Tpk1 and Tpk2 of Candida albicans PKA have non-redundant roles in stress response and glycogen storage
(John Wiley & Sons Ltd, 2009-12)
Candida albicans cAMP-dependent protein kinase (PKA) is coded by two catalytic subunits (TPK1 and TPK2) and one regulatory subunit (BCY1). In this organism the cAMP/PKA signalling pathway mediates basic cellular processes, ...
Chromatin remodeling and transcription of the TPK1 subunit of PKA during stress in Saccharomyces cerevisiae
(Elsevier Science, 2020-09)
In response to environmental changes cells rapidly rearrange their gene expression pattern in order to adapt to the new conditions. Chromatin remodeling is critical for this process playing a major role in the induction ...
Cross regulation between Candida albicans catalytic and regulatory subunits of protein kinase A
(Elsevier, 2012-01)
In the pathogen Candida albicans protein kinase A (PKA) catalytic subunit is encoded by two genes TPK1 and TPK2 and the regulatory subunit by one gene, BCY1. PKA mediates several cellular processes such as cell cycle ...
Regulation of PKA activity by an autophosphorylation mechanism in Saccharomyces cerevisiae
(Portland Press, 2014-09)
PKA (cAMP-dependent protein kinase) activity, as well as that of other AGC members, is regulated by multiple phosphorylations of its catalytic subunits. In Saccharomyces cerevisiae, the PKA regulatory subunit is encoded ...
A prion-like domain of Tpk2 catalytic subunit of protein kinase A modulates P-body formation in response to stress in budding yeast
(Elsevier Science, 2021-01)
Low complexity regions are involved in the assembly and disassembly of P-bodies (PBs). Saccharomyces cerevisiae contains three genes encoding the protein kinase A (PKA) catalytic subunit: TPK1, TPK2 and TPK3. Tpk2 and Tpk3 ...
The activation loop of PKA catalytic isoforms is differentially phosphorylated by Pkh protein kinases in Saccharomyces cerevisiae
(Portland Press, 2012-09)
PDK1 (phosphoinositide-dependent protein kinase 1) phosphorylates and activates PKA (cAMP-dependent protein kinase) in vitro. Docking of the HM (hydrophobic motif) in the C-terminal tail of the PKA catalytic subunits on ...
Interacción de la proteína quinasa dependiente de cAMP con sus genes blanco en Saccharomyces cerevisiaeInteraction of cAMP-dependent Protein Kinase with its target genes in Saccharomyces cerevisiae
(Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires, 2014)
Estudios bioquímicos de las isoformas Tpk1p y Tpk2p de la PKA de Candida albicans
(Universidad de Belgrano. Facultad de Ciencias Exactas y Naturales., 2005)
Trabajos previos de nuestro laboratorio y de otros han demostrado que la vía de señalización celular
AMPc/PKA está involucrada en la respuesta de C. albicans a alguno de los factores ambientales que
...
Voltage-dependent gating of SV channel TPC1 confers vacuole excitability
(2019)
In contrast to the plasma membrane, the vacuole membrane has not yet been associated with electrical excitation of plants. Here, we show that mesophyll vacuoles from Arabidopsis sense and control the membrane potential ...