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Injectable thermosensitive gels based in Poloxamer as modified drug release systems for veterinary use
(Colegio Farmaceuticos Provincia de Buenos Aires, 2010-12)
The purpose of this work is to explore the potential of combining poloxamer 407 and carrageenan for its utilization in an injectable depot drug release system. Reverse thermal gelation of these formulations allow the local ...
Synthesis, characterization and solution properties of amphiphilic N-isopropylacrylamide-poly(ethylene glycol)-dodecyl methacrylate thermosensitive polymers
(Elsevier B.V., 2005-07-15)
Terpolymers of N-isopropylacrylamide, dodecyl methacrylate (DOMA) and poly(ethylene glycol) (PEG) methacrylate, were synthesized by random copolymerization, and the composition was controlled to achieve systems having ...
Synthesis, characterization and solution properties of amphiphilic N-isopropylacrylamide-poly(ethylene glycol)-dodecyl methacrylate thermosensitive polymers
(Elsevier B.V., 2005-07-15)
Terpolymers of N-isopropylacrylamide, dodecyl methacrylate (DOMA) and poly(ethylene glycol) (PEG) methacrylate, were synthesized by random copolymerization, and the composition was controlled to achieve systems having ...
Application of simultaneous multiple response optimization in the preparation of thermosensitive chitosan/glycerophosphate hydrogels
(Springer, 2016-09)
The parameters affecting the sol/gel transition of chitosan-based thermogelling systems, their final proper-ties and structure have been reported. Nevertheless, equa-tions that define this relationship specific for a ...
Evaluation of the performance of an ophthalmic thermosensitive hydrogel containing combination of suramin and bevacizumab
(Bentham Science Publishers, 2016-12)
Suramab (SUM) is a new pharmaceutical combination made up of suramine (SUR) and bevacizumab (BVM), which showed a high synergistic effect when administered jointly. As the pharmaceutical vehicle, poloxamer aqueous dispersions ...
Thermosensitive poloxamer-based injectables as controlled drug release platforms for veterinary use: development and in-vitro evaluation
(International Research Journals Publishing House, 2011-09)
The aim of this work was to explore the potential of combining two different poloxamers (P407 and P188) with κ-carrageenan and sodium chloride for their utilization in the design of thermosensitive injectable depot systems ...
Progesterone loaded thermosensitive hydrogel for vaginal application: Formulation and in vitro comparison with commercial product
(Elsevier B.V., 2019-09)
Progesterone (PGT) is a natural hormone that stimulates and regulates various important functions, such as the preparation of the female body for conception and pregnancy. Due to its low water solubility, it is administered ...