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Genetic components of human pain sensitivity: A protocol for a genome-wide association study of experimental pain in healthy volunteers
(BMJ Publishing Group, 2019)
INTRODUCTION: Pain constitutes a major component of the global burden of diseases. Recent studies suggest a strong genetic contribution to pain susceptibility and severity. Whereas most of the available evidence relies on ...
A new experimental model of muscle pain in humans based on short-wave diathermy
(Elsevier, 2019-10)
Background: Experimental models of pain in humans are crucial for understanding pain mechanisms. The most often used muscle pain models involve the injection of algesic substances, such as hypertonic saline solution or ...
A systematic review of treatment of Painful Diabetic Neuropathy by Pain Phenotype versus treatment Based on Medical comorbidities
(Frontiers Media Sa, 2017)
Background: Painful diabetic neuropathy (PDN) is a serious, polymorphic, and prevalent complication of diabetes mellitus. Most PDN treatment guidelines recommend a selection of drugs based on patient comorbidities. Despite ...
Frequency of musculoskeletal pain and thermal comfort in students of dentistry
(Universidade Federal de Santa Maria, 2018)
Cytokine Levels in Neural Pain in Leprosy
(Frontiers Media, 2021)
People with musculoskeletal shoulder pain demonstrate no signs of altered pain processing
(Facultad de Ciencias de la Salud, 2019)
Background: Central sensitisation may contribute to persistent musculoskeletal shoulder pain. Few studies have provided a comprehensive sensory and psychosocial evaluation of this population. Objective: To comprehensively ...
Potential novel strategies for the treatment of dental pulp-derived pain: pharmacological approaches and beyond
(2019)
The diagnosis and management of pain is an everyday occurrence in dentistry, and its
effective control is essential to ensure the wellbeing of patients. Most tooth-associated
pain originates from the dental pulp, a highly ...
Rat bone marrow stromal cells and oligonucleotides in pain research
(Humana Press, 2010-02-13)
In the last years, significant progress has been made in the medical treatment of pain. However, pathological pains, such us neuropathic pain, remain refractory to the currently available analgesics. Therefore, new therapeutic ...
Trigeminal pain and quantitative sensory testing in painful peripheral diabetic neuropathy
(PERGAMON-ELSEVIER SCIENCE LTD, 2010)
Objective: To evaluate patients with Diabetes Mellitus type 2 and painful peripheral neuropathy in order to investigate oral complaints and facial somatosensory findings. Research design and methods: Case-control study; ...
Pain hypersensitivity induced by paradoxical sleep deprivation is not due to altered binding to brain mu-opioid receptors
(Elsevier B.V., 2007-03-28)
Previous studies have established a relationship between sleep disruption and pain, and it has been suggested that hyperalgesia induced by paradoxical sleep deprivation (PSD) could be due to a reduction of opioidergic-ne ...