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Role of dihydrotestosterone (DHT) on TGF-β1 signaling pathway in epithelial ovarian cancer cells
(Springer Verlag, 2016)
© 2015, The Author(s).Purpose: One of the hypotheses regarding the genesis of epithelial ovarian cancer involves the action of androgens on the proliferation of epithelial ovarian cells, as well as inclusion cysts. The ...
TGF-β1 prevents simulated ischemia/reperfusion-induced cardiac fibroblast apoptosis by activation of both canonical and non-canonical signaling pathways
(2013)
Ischemia/reperfusion injury is a major cause of myocardial death. In the heart, cardiac fibroblasts play a
critical role in healing post myocardial infarction. TGF-β1 has shown cardioprotective effects in cardiac damage; ...
The TGF-β Pathway as an Emerging Target for Chagas Disease Therapy
(American Society for Clinical Pharmacology and Therapeutics, 2017)
Role of dihydrotestosterone (DHT) on TGF‑β1 signaling pathway in epithelial ovarian cancer cells
(Springer, 2016)
Purpose One of the hypotheses regarding the genesis of epithelial ovarian cancer involves the action of androgens on the proliferation of epithelial ovarian cells, as well as inclusion cysts. The purpose of the present ...
TGF-β pro-oligodendrogenic effects on adult SVZ progenitor cultures and its interaction with the Notch signaling pathway
(Wiley-liss, Div John Wiley & Sons Inc, 2018-02)
Adult neural progenitor cells (NPCs) are capable of differentiating into neurons, astrocytes, and oligodendrocytes throughout life. Notch and transforming growth factor β1 (TGF‐β) signaling pathways play critical roles in ...
Involvement of KLF14 and egr-1 in the TGF-beta1 action on Leydig cell proliferation
(Academic Press Ltd - Elsevier Science Ltd, 2013-02)
Transforming growth factor β1 (TGF-β1) is a pleiotropic cytokine that modulates cell homeostasis. In Leydig cells, TGF-β1 exerts stimulatory and inhibitory effect depending on the type I receptor involved in the signaling ...
Extracellular matrix remodeling and TGF-β1/Smad signaling in diabetic colon mucosa
(Academic Press Ltd - Elsevier Science Ltd, 2017-12)
Diabetes is associated with metabolic and functional alterations in the gut. Using an experimental model of streptozotocin (STZ)-induced diabetes in rodents, we analyzed the extracellular matrix (ECM) and TGF-β/Smad signaling ...