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Larvicidal study of tetrahydropyrimidine scaffolds against Anopheles arabiensis and structural insight by single crystal X-ray studies

Bairagi, Keshab M.; Venugopala, Katharigatta N.; Mondal, Pradip Kumar; Gleiser, Raquel M.; Chopra, Deepak; Garcia, Daniel Asmed; Odhav, Bharti; Nayak, Susanta K. (Wiley Blackwell Publishing, Inc, 2018-12-20)

A series of methyl or ethyl 4-(substitutedphenyl/pyridyl)-6-methyl-2-oxo/thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (HPM) analogues 4a–g were synthesized and evaluated for larvicidal activity against Anopheles ...