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Clasificación de quimiosensibilidad tumoral en muestras del proyecto TCGA mediante la integración de datos genómicos del cáncer
(2019-08)
La enfermedad del cáncer causa millones de muertes en todo el mundo y miles en Costa Rica, y el tratamiento del cáncer causa también una carga económica inmensa en el sistema de seguridad social porque las drogas contra ...
Inverse expression of survivin and reprimo correlates with poor patient prognosis in gastric cancer
(Impact Journals LLC, 2018)
© Cerda-Opazo et al. BACKGROUND: The objective of the study was to determine the relationship between Survivin and Reprimo transcript/protein expression levels, and gastric cancer outcome. METHODS: In silico correlations ...
Epigenetic silencing of neurofilament genes promotes an aggressive phenotype in breast cancer
(2015-01-01)
Neurofilament heavy polypeptide (NEFH) has recently been identified as a candidate DNA hypermethylated gene within the functional breast cancer hypermethylome. NEFH exists in a complex with neurofilament medium polypeptide ...
Nc886 is epigenetically repressed in prostate cancer and acts as a tumor suppressor through the inhibition of cell growth
(BioMed Central, 2018)
Abstract
Background
Nc886 is a 102 bp non-coding RNA transcript initially classified as a microRNA precursor (Pre-miR-886), later as a divergent homologue of the vault RNAs ...
The expression landscape of cachexia-inducing factors in human cancers
(2020-08-01)
Background: Cachexia is a multifactorial syndrome highly associated with specific tumour types, but the causes of variation in cachexia prevalence and severity are unknown. While circulating plasma mediators (soluble ...
Intratumor heterogeneity index of breast carcinomas based on DNA methylation profiles
(BioMed Central, 2019-04)
Background: Cancer cells evolve and constitute heterogeneous populations that fluctuate in space and time and are subjected to selection generating intratumor heterogeneity. This phenomenon is determined by the acquisition ...
Unraveling the oral cancer lncRNAome: Identification of novel lncRNAs associated with malignant progression and HPV infection
(Elsevier Science, 2016-08)
SummaryObjectives The role of long non-coding RNA (lncRNA) expression in human head and neck squamous cell carcinoma (HNSCC) is still poorly understood. In this study, we aimed at establishing the onco-lncRNAome profiling ...
Inverse expression of survivin and reprimo correlates with poor patient prognosis in gastric cancer
(Impact Journals, 2018-02)
BACKGROUND: The objective of the study was to determine the relationship between Survivin and Reprimo transcript/protein expression levels, and gastric cancer outcome. METHODS: In silico correlations between an agnostic ...