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The YAP/TAZ Signaling Pathway in the Tumor Microenvironment and Carcinogenesis: Current Knowledge and Therapeutic Promises
(MDPI, 2022)
The yes-associated protein (YAP) and the transcriptional coactivator with PDZ-binding motif (TAZ) are transcriptional coactivators, members of the Hippo signaling pathway, which play a critical role in cell growth regulation, ...
Wnt5a Signaling in Gastric Cancer
(Frontiers Media S.A., 2020)
Phosphorylation regulates the bound structure of an intrinsically disordered protein: The p53-TAZ2 case
(Public Library of Science, 2016-01-07)
Disordered regions and Intrinsically Disordered Proteins (IDPs) are involved in critical cellular processes and may acquire a stable three-dimensional structure only upon binding to their partners. IDPs may follow a ...
TAZ Controls Helicobacter pylori-Induced Epithelial–Mesenchymal Transition and Cancer Stem Cell-Like Invasive and Tumorigenic Properties
(2020)
Helicobacter pylori infection, the main risk factor for gastric cancer (GC), leads to an epithelial–mesenchymal transition (EMT) of gastric epithelium contributing to gastric cancer stem cell (CSC) emergence. The Hippo ...
GTSE1: a novel TEAD4-E2F1 target gene involved in cell protrusions formation in triple-negative breast cancer cell models
(Impact Journals, 2017-06)
Dissemination of cancer cells from the primary tumors to distant organs represents the main cause of death in cancer patients. GTSE1 over-expression has been reported as a potential marker for metastasis in various types ...
Influência da via hippo no reparo da mucosite oral quimicamente induzida em modelo murino submetida a tratamento com laser, geleia real ou própolis
(Universidade Federal do Rio Grande do NorteBrasilUFRNPROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS ODONTOLÓGICAS, 2023)
Bone fracture healing: perspectives according to molecular basis
(Springer Tokyo, 2021-05)
Fractures have a great impact on health all around the world and with fracture healing optimization; this problem could be resolved partially. To make a practical contribution to this issue, the knowledge of bone tissue, ...
Presencia de marcadores de transición epitelio-mesénquima por inmunohistoquímica en osteosarcoma pediátrico y asociación con desenlaces clínicos
(Universidad Nacional de ColombiaBogotá - Medicina - Especialidad en Oncohematología PediátricaDepartamento de PediatríaFacultad de MedicinaBogotá, ColombiaUniversidad Nacional de Colombia - Sede Bogotá, 2021-12)
Introducción: La transición epitelio-mesénquima (TEM) es la capacidad celular de cambiar su fenotipo original de forma transitoria y ha sido identificado como un mecanismo tumoral asociado con características clínicas ...