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Effects of chronic carvedilol administration on blood pressure variability and target organ injury in rats with sinoaortic denervationEfectos de la administración crónica de carvedilol sobre la variabilidad de la presión arterial y el daño de órgano blanco en ratas con desnervación sinoaórtica
(Sociedad Argentina de Cardiología, 2015-06)
Background: Increased blood pressure variability is a novel risk factor for the development of target organ injury both in hypertensive and normotensive subjects, so its reduction should be considered as a new therapeutic ...
THE ROLE OF INNATE IMMUNITY IN SEPTIC ACUTE KIDNEY INJURIES
(LIPPINCOTT WILLIAMS & WILKINS, 2010)
Acute kidney injury (AKI) is an important clinical syndrome characterized by abnormalities in the hydroelectrolytic balance. Because of high rates of morbidity and mortality (from 15% to 60%) associated with AKI, the study ...
Midgut and fat body: Multisystemic action of pyriproxyfen on non-target organism Ceraeochrysa claveri (Neuroptera: Chrysopidae)
(2022-01-15)
Morphological tools can assist in the evaluation of effects of insecticides on non-target insects. Pyriproxyfen, a juvenile hormone analog, is known to interfere with growth and metamorphosis of insects. However, there are ...
Deregulation of adipokines related to target organ damage on resistant hypertension
(Nature Publishing GroupLondonInglaterra, 2014)
Gasdermin D inhibition prevents multiple organ dysfunction during sepsis by blocking NET formation
(2021-12-23)
Multiple organ dysfunction is the most severe outcome of sepsis progression and is highly correlated with a worse prognosis. Excessive neutrophil extracellular traps (NETs) are critical players in the development of organ ...
Role of oxidative stress in renal transplantation: bases for an n-3 PUFA strategy against delayed graft function
(Bentham Science Publ Ltd., 2017)
Renal transplantation (RT) is considered the "gold standard" treatment for end-stage renal disease patients. Efforts should be made to reduce ischaemia-reperfusion (IR) injury, which unavoidably occurs in RT as long as ...
Annexin-A1 peptide down-regulates the leukocyte recruitment and up-regulates interleukin-10 release into lung after intestinal ischemia-reperfusion in mice
(2013-03-15)
Background: Intestinal ischemia/reperfusion (IR) injury is a serious and triggering event in the development of remote organ dysfunction, from which the lung is the main target. This condition is characterized by intense ...