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Detection of tamoxifen metabolites by GC-MSD
(PRESTON PUBLICATIONS INC, 2004-11)
Tamoxifen is an antiestrogen used in the adjuvant endocrine
therapy of early breast cancer and malignant breast disorders. It is
also used in women with anovulatory infertility caused by its
stimulating effect on the ...
Estrogenic activity of tamoxifen on normal mammary parenchyma in the luteal phase of the menstrual cycle
(Elsevier B.V., 1997-01-01)
Objectives: Tamoxifen, an anti-estrogenic drug used in the adjuvant treatment of breast cancer, deserves more investigation for the determination of its efficacy as a prophylactic agent against breast cancer in high risk ...
Effects of tamoxifen on Doppler velocimetry parameters of periurethral vessels in postmenopausal women
(Springer, 2005-02-01)
The purpose of the present study was to assess the effect of tamoxifen on periurethral vessels by Doppler velocimetry examination. Increase in the number of these vessels as well as decrease in resistance and pulsatility ...
Non-genomic actions of estradiol and 4-OH-tamoxifen on murine breast cancer cells
(Spandidos Publications, 2015-01)
Estrogens and tamoxifen do not only exert their effects at the genomic level, but also play a role at the cell membrane activating downstream signaling pathways. We recently characterized an estrogen receptor-positive ...
Assessment of Vascular Effects of Tamoxifen and Its Metabolites on the Rat Perfused Hindquarter Vascular Bed
(WILEY-BLACKWELL PUBLISHING, INC, 2009)
Tamoxifen has been suggested to produce beneficial cardiovascular effects, although the mechanisms for these effects are not fully known. Moreover, although tamoxifen metabolites may exhibit 30-100 times higher potency ...
Adsorptive potentiometric stripping analysis of trace tamoxifen at a glassy carbon electrode
(Elsevier B.V., 1997-12-19)
A highly sensitive adsorptive stripping procedure for trace measurement of the anticancer drug tamoxifen is described. The method is based on controlled adsorptive accumulation of the drug at an electrochemically treated ...
Adsorptive potentiometric stripping analysis of trace tamoxifen at a glassy carbon electrode
(Elsevier B.V., 1997-12-19)
A highly sensitive adsorptive stripping procedure for trace measurement of the anticancer drug tamoxifen is described. The method is based on controlled adsorptive accumulation of the drug at an electrochemically treated ...
Morphological action of tamoxifen in the endometrium of persistent estrous rats
(Munksgaard Int Publ Ltd, 1996-09-01)
Background. the aim of this study was to evaluate the action of tamoxifen on the endometrium in stales of chronic anovulation.Methods. Thirty-eight rats inducted to persistent estrous (testosterone propionate) confirmed ...
Tamoxifen use for the management of mania: a review of current preclinical evidence
(Springer, 2014-02-01)
Preliminary data on the efficacy of tamoxifen in reducing manic symptoms of bipolar disorder (BD) suggest that this agent may be a potential treatment for the management of this psychiatric disorder. However, the antimanic ...