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DEB TACE for Intermediate and advanced HCC - Initial Experience in a Brazilian Cancer Center
(BioMed Central, 2018)
A combinational approach to restore cytokine balance and to inhibit virus growth may promote patient recovery in severe COVID-19 cases
The COVID-19 pandemic has led to twin public health and economic crises around the world. Not only has it cost hundreds of thousands of lives but also severely impacted livelihoods and placed enormous strain on community ...
Involvement of TACE/ADAM17 and ADAM10 in etoposide-induced apoptosis of germ cells in rat spermatogenesis
(WILEY-BLACKWELL, 2012-02)
Germ cell apoptosis is important to regulate sperm production in the mammalian testis, but the molecular mechanisms underlying apoptosis are still poorly understood. We have recently shown that in vitro, etoposide induces ...
Efeito da inibição da clivagem do fator de necrose tumoral (TNF) em modelo de isquemia e reperfusão intestinal
(Universidade Federal de Minas GeraisUFMG, 2007-02-27)
TNF-á plays an important role in reperfusion-induced tissue injury andlethality. Here, we assessed the effect of PKF242-484 and PKF241-466, two dual inhibitors of TNF-á converting enzyme (TACE) and matrixmetalloproteinases ...
TACE/ADAM17 is involved in germ cell apoptosis during rat spermatogenesis
(2010)
The pathways leading to male germ cell apoptosis in vivo are poorly understood, but are highly relevant for the comprehension of sperm production regulation by the testis. In this work, we show the evidence of a mechanism ...