Microbes can be engineered to act like living therapeutics designed to perform specific actions in the human body. From fighting and preventing infections to eliminating tumors and treating metabolic disorders, engineered ...

A vast microbial community lives on and within the human body. Recent advances in microbiome studies have shown how some living bacteria can positively influence human health. The findings have raised interest in engineering ...

The leishmaniasis is a spectral disease caused by the protozoan Leishmania spp., which threatens millions of people worldwide. Current treatments exhibit high toxicity, and there is no vaccine available. The need for new ...

In synthetic (or Phase II or conjugation) reactions, an endogenous or exogenous compound (the substrate of the reaction) is coupled to an endogenous conjugating moiety (sometimes called endocon). The conjugating moiety is ...