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Mostrando ítems 1-10 de 94
Reprogramação do metabolismo de purina na bactéria Bacillus subtilis por tecnologia de pequenos RNAs não codificadores (sRNAs)
(Universidade Estadual Paulista (Unesp), 2019-07-25)
As técnicas mais usadas atualmente para alterar o fluxo metabólico por uma determinada via são a deleção e/ou inserção de sequências regulatórias ou genes no cromossomo bacteriano. Estes são métodos que alteram permanentemente ...
Targeting riboswitches with synthetic small RNAs for metabolic engineering
(2021-11-01)
Our growing knowledge of the diversity of non-coding RNAs in natural systems and our deepening knowledge of RNA folding and function have fomented the rational design of RNA regulators. Based on that knowledge, we designed ...
Non-canonical roles of tRNAs and tRNA mimics in bacterial cell biology
(Wiley-Blackwell, 2016)
Transfer RNAs (tRNAs) are the macromolecules that transfer activated amino acids from aminoacyl-tRNA synthetases to the ribosome, where they are used for the mRNA guided synthesis of proteins. Transfer RNAs are ancient ...
Modulation of the Proteostasis Machinery to Overcome Stress Caused by Diminished Levels of t6A‐Modified tRNAs in Drosophila
(2017)
Transfer RNAs (tRNAs) harbor a subset of post-transcriptional modifications required for structural stability or decoding function. N6-threonylcarbamoyladenosine (t6A) is a universally conserved modification found at ...
Non-coding transcript in T cells (NTT): Antisense transcript activates PKR and NF-kappa B in human lymphocytes
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2008)
T cell activation is a complex process involving many steps and the role played by the non-protein-coding RNAs (ncRNAs) in this phenomenon is still unclear. The non-coding T cells transcript (NTT) is differentially expressed ...
Aplicação de um sistema sintético de controle da expressão gênica para a produção de vitamina B2 em Bacillus subtilis
(Universidade Estadual Paulista (Unesp), 2021-08-31)
A riboflavina é uma vitamina solúvel em água que possui papel essencial no crescimento e desenvolvimento celular, sua produção anual total é de aproximadamente 9000 toneladas, sendo um bioprocesso rentável. As cepas ...
Elongator subunit 3 (Elp3) Is required for Zebrafish trunk development
(MDPI, 2020)
Transfer RNAs (tRNAs) are the most post-transcriptionally modified RNA species. Some of these modifications, especially the ones located in the anti-codon loop, are required for decoding capabilities of tRNAs. Such is the ...
Bacteriófagos recombinantes e miRNAs como estratégias para o controle de Spodoptera frugiperdaRecombinant bacteriophages and miRNAs as strategies for the Spodoptera frugiperda control
(Universidade Federal de UberlândiaBrasilPrograma de Pós-graduação em Biotecnologia, 2019)