Now showing items 1-10 of 618
The influence of connectivity on the firing rate in a neuronal network with electrical and chemical synapses
(ELSEVIER SCIENCE BVAMSTERDAM, 2012-02-01)
We study the firing rate properties of a cellular automaton model for a neuronal network with chemical synapses. We propose a simple mechanism in which the nonlocal connections are included, through electrical and chemical ...
New insights to the functional role of the T cell-Antigen Presenting Cell immunological synapse
(Sociedad de Biología de Chile, 2002)
Neurotrophin-3 regulates ribbon synapse density in the cochlea and induces synapse regeneration after acoustic trauma
(eLife Sciences Publications, 2014-10)
Neurotrophin-3 (Ntf3) and brain derived neurotrophic factor (Bdnf) are critical for sensory neuron survival and the establishment of neuronal projections to sensory epithelia in the embryonic inner ear, but their postnatal ...
Dendrodendritic synapses in the mouse olfactory bulb external plexiform layer
Odor information relayed by olfactory bulb projection neurons, mitral and tufted cells (M/T), is modulated by pairs of reciprocal dendrodendritic synaptic circuits in the external plexiform layer (EPL). Interneurons, which ...
Protein synthesis at the synapse: Developmental changes, subcellular localization and regional distribution of polypeptides synthesized in isolated dendritic fragments
This study evaluated local protein synthesis in subcellular fractions of pinched-off dendrites (synaptodendrosomes) from different brain regions and at different developmental ages. Synaptodendrosomes were labeled with ...
Recent advances in brain physiology and cognitive processing
The discovery of participation of astrocytes as active elements in glutamatergic tripartite synapses (composed by functional units of two neurons and one astrocyte) has led to the construction of models of cognitive ...
Cochlear hair cells: The sound-sensing machines
The sensory epithelium of the mammalian inner ear contains two types of mechanosensory cells:inner (IHC) and outer hair cells (OHC). They both transduce mechanical force generated by soundwaves into electrical signals. In ...
Glycoprotein synthesis at the synapse: fractionation of polypeptides synthesized within isolated dendritic fragments by concanavalin A affinity chromatography
The synthesis of glycosylated proteins at postsynaptic sites was evaluated by combining metabolic labeling of isolated pinched-off dendritic fragments (synaptodendrosomes) with glycoprotein isolation by Con A affinity ...
Mechanisms of synaptic depression at the hair cell ribbon synapse that support auditory nerve function
(National Academy of Sciences, 2017-09)
Inner hair cells (IHCs) in the cochlea are the mammalian phono-receptors, transducing sound energy into graded changes in membrane potentials, the so called “receptor potentials.” Ribbon synapses between IHCs and auditory ...