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Novel sulfamides and sulfamates derived from amino esters: Synthetic studies and anticonvulsant activity
(Elsevier Science, 2016-03)
We report herein the design and optimization of a novel series of sulfamides and sulfamates derived from amino esters with anticonvulsant properties. The structures were designed based on the pharmacophoric pattern previously ...
Intramolecular Phl=O mediated copper-catalyzed aziridination of unsaturated sulfamates: A new direct access to polysubstituted amines from simple homoallylic alcohols
(American Chemical Society, 2002-07)
(Matrix presented) Olefinic sulfamates derived from primary and secondary alcohols undergo intramolecular copper-catalyzed aziridination in the presence of iodosylbenzene to afford novel bicyclic fused aziridines. The ...
Improving the carbonic anhydrase inhibition profile of the sulfamoylphenyl pharmacophore by attachment of carbohydrate moieties
(Academic Press Inc Elsevier Science, 2018-02)
One of the most successful approaches for designing carbonic anhydrase (CA, EC 4.2.1.1) inhibitors was denominated ‘the sugar approach’. The sugar approach consists in attaching different carbohydrates to CA inhibiting ...
Análisis de la resistencia bacteriana en pacientes de la unidad de cuidados intensivos del hospital regional Guillermo Días de la Vega, Abancay
(Universidad Alas PeruanasPE, 2017)
Objetivos: Analizar la resistencia bacteriana en pacientes de la unidad de cuidados intensivos del Hospital Regional Guillermo Díaz de la Vega, Abancay
Metodología: El tipo de investigación fue prospectiva, transversal ...
Cinética da redução de NOx pelo ácido amino sulfâmico : modelagem e desenvolvimento
(Universidade Federal de Pernambuco, 2014)
Glycosidic carbonic anhydrase IX inhibitors: a sweet approach against cancer
(Elsevier, 2013-03)
Targeting tumour associated carbonic anhydrase (CA, EC 4.2.1.1) isoforms IX and XII is now considered as a pertinent approach for the development of new cancer therapeutics against hypoxic tumours. In the last period, with ...
Caracterização de níquel eletrodepositado em substrato de cobre
(Universidade Federal de Minas GeraisUFMG, 2006-04-27)
Tribological properties of engineering materials are enhanced with the use of coatings. In the steel industry, nickel coatings on copper have increased the useful life of continuous ingot casting molds. The electrodeposited ...
Effect of Sodium Cyclamate on the Rat Fetal Exocrine Pancreas: a Karyometric and Stereological Study
(SOC CHILENA ANATOMIA, 2010)
The cyclamate, a sweetner substance derived from N-cyclo-hexyl-sulfamic acid, is largely utilized as a non-caloric artificial edulcorant in foods and beverages as well as in the pharmaceutical industry. The objective of ...
Inhibition pattern of sulfamide-related compounds in binding to carbonic anhydrase isoforms I, II, VII, XII and XIV
(Pergamon-Elsevier Science Ltd, 2013-03)
A set of sulfamides and sulfamates were synthesized and tested against several isoforms of carbonic anhydrase: CA I, CA II, CA VII, CA XII and CA XIV. The biological assays showed a broad range of inhibitory activity, and ...