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Hexose transporter glut1 harbors several distinct regulatory binding sites for flavones and tyrphostins
(AMER CHEMICAL SOC, 2011)
The facilitative hexose transporter GLUT1 activity is blocked by tyrosine kinase inhibitors that include natural products such as flavones and isoflavones and synthetic compounds such as tyrphostins, molecules that are ...
Spermiogenesis in Melanophryniscus cambaraensis (Amphibia, Anura, Bufonidae): ultrastructural and cytochemical studies of carbohydrates using lectins
(Faculty PressCambridgeInglaterra, 2001)
B-lactoglobulin's conformational requirements for ligand binding at the calyx and the dimer interphase : a flexible docking study
(Public Library of Science, 2013)
Mapping of a Regulatory Site of the Escherichia coli ADP-Glucose Pyrophosphorylase
(Frontiers Media S.A., 2019-09)
The enzyme ADP-glucose pyrophosphorylase (ADP-Glc PPase) controls the biosynthesis of glycogen in bacteria and starch in plants. It is regulated by various activators in different organisms according to their metabolic ...
Structure and catalytic mechanism of glucosamine 6-phosphate deaminase from Escherichia coli at 2.1 Å resolution
(1995-12-01)
Background: Glucosamine 6-phosphate deaminase from Escherichia coli is an allosteric hexameric enzyme which catalyzes the reversible conversion of D-glucosamine 6-phosphate into D-fructose 6-phosphate and ammonium ion and ...
Structure and catalytic mechanism of glucosamine 6-phosphate deaminase from Escherichia coli at 2.1 Å resolution
(1995-12-01)
Background: Glucosamine 6-phosphate deaminase from Escherichia coli is an allosteric hexameric enzyme which catalyzes the reversible conversion of D-glucosamine 6-phosphate into D-fructose 6-phosphate and ammonium ion and ...
How cholesterol interacts with membrane proteins : an exploration of cholesterol-binding sites including CRAC, CARC, and tilted domains
(Frontiers, 2013)
Abstract: The plasma membrane of eukaryotic cells contains several types of lipids displaying high biochemical variability in both their apolar moiety (e.g., the acyl chain of glycerolipids) and their polar head (e.g., the ...
Structure of an ancestral ADP-dependent kinase with fructose-6P reveals key residues for binding, catalysis, and ligand-induced conformational changes
(American Society for Biochemistry and Molecular Biology, 2021)
ADP-dependent kinases were first described in archaea, although their presence has also been reported in bacteria and eukaryotes (human and mouse). This enzyme family comprises three substrate specificities; specific ...