Buscar
Mostrando ítems 1-10 de 150
Gentle handling temporarily increases c-Fos in the substantia nigra pars compacta
(Associação Brasileira de Divulgação Científica, 2008-10-01)
Dopaminergic neurotransmission is involved in the regulation of sleep. In particular, the nigrostriatal pathway is an important center of sleep regulation. We hypothesized that dopaminergic neurons located in substantia ...
Evaluation of estrogen neuroprotective effect on nigrostriatal dopaminergic neurons following 6-hydroxydopamine injection into the substantia nigra pars compacta or the medial forebrain bundle
(SPRINGER/PLENUM PUBLISHERS, 2008)
Studies involving estrogen treatment of ovariectomized rats or mice have attributed to this hormone a neuroprotective effect on the substantia nigra pars compacta (SNpc) neurons. We investigated the effect of estradiol ...
Defining the molecular composition of the axon initial segment of substantia nigra dopaminergic neurons
(2014)
Dopaminergic neurons (DANs) of the substantia nigra pars compacta (SNc) play a
critical role in motor control, reward mechanisms, and learning. Dopamine release in
the striatum, as well as in other brain regions, is tightly ...
Hemiparkinsonian rats rotate toward the side with the weaker dopaminergic neurotransmission
(ELSEVIER SCIENCE BV, 2008)
Rats with unilateral lesion of the substantia nigra pars compacta (SNpc) have been used as a model of Parkinson`s disease. Depending on the lesion protocol and on the drug challenge, these rats rotate in opposite directions. ...
Microdialysis study of striatal dopamine in MPTP-hemilesioned rats challenged with apomorphine and amphetamine
(ELSEVIER SCIENCE BV, 2010)
Motor impairments of Parkinson`s disease (PD) appear only after the loss of more than 70% of the DAergic neurons of the substantia nigra pars compacta (SNc). An earlier phase of this disease can be modeled in rats that ...
Rol de la substantia nigra y el núcleo subtalámico en la respuesta de sobresalto acústico e inhibición prepulso en ratas: una revisión sistemática
(Universidad de los AndesPsicologíaFacultad de Ciencias SocialesDepartamento de Psicología, 2023-02-09)
La respuesta de sobresalto acústico e inhibición prepulso ha sido ampliamente estudiada en esquizofrenia, pues es una medida usada para evaluar alteraciones en el filtrado sensoriomotor. Sin embargo, en pacientes con ...
Effects of Allogeneic Bone Marrow Derived Mesenchymal Stromal Cell Therapy on Voiding Function in a Rat Model of Parkinson Disease
(Elsevier B.V., 2014-03-01)
Purpose: Cellular therapy induced transient urodynamic improvement in a rat model of Parkinson disease in which bladder dysfunction was noted after unilateral injection of 6-hydroxydopamine into the medial forebrain bundle. ...