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DNA Double-Strand Breaks: A Double-Edged Sword for Trypanosomatids
(2021-04-15)
For nearly all eukaryotic cells, stochastic DNA double-strand breaks (DSBs) are one of the most deleterious types of DNA lesions. DSB processing and repair can cause sequence deletions, loss of heterozygosity, and chromosome ...
The invariance of the total direct DNA strand break yield
(Amer Assoc Physicists Medicine Amer Inst PhysicsMelvilleEUA, 2011)
The natural absence of RPA1N domain did not impair Leishmania amazonensis RPA-1 participation in DNA damage response and telomere protection.
(2013-04-01)
We have previously shown that the subunit 1 of Leishmania amazonensis RPA (LaRPA-1) alone binds the G-rich telomeric strand and is structurally different from other RPA-1. It is analogous to telomere end-binding proteins ...
Human syndromes with genomic instability and multiprotein machines that repair DNA double-strand breaks
(2003)
The present report deals with the functional relationships among protein complexes which, when mutated, are responsible for four human syndromes displaying cancer proneness, and whose cells are deficient in DNA double-strand ...
Protamine deficiency in a nelore bull with high levels of dna strand breaks: case report
(Wiley-Blackwell, 2011-09-01)
Protamine deficiency in a nelore bull with high levels of dna strand breaks: case report
(Wiley-Blackwell, 2011-09-01)
Subtelomeric I-scei-mediated Double-strand Breaks Are Repaired By Homologous Recombination In Trypanosoma Cruzi
(Frontiers Research Foundation, 2016)
Subtelomeric I-scel-mediated Double-strand Breaks Are Repaired By Homologous Recombination In Trypanosoma Cruzi
(Frontiers Media SALausanne, 2016)