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Diastereoselective synthesis of spirodihydrobenzofuran analogues of the natural product filifolinol
(Wiley, 2020)
Filifolinol is a natural occurring spirodihydrobenzofuran isolated from the resinous exudates of Heliotropium filifolium, a Chilean endemic shrub. Filifolinol and some of its derivatives have shown interesting biological ...
New Spiro-acridines: Dna Interaction, Antiproliferative Activity And Inhibition Of Human Dna Topoisomerases
(Elsevier Science BVAmsterdam, 2016)
Novos Espirocromenil-Trifluoretanonas a partir de Reações de Trifluoracetilação de Adutos de Kabbe e seus Espiro[diidrocromeno-cicloalcan]pirazóis e Isoxazóis Derivados
(Universidade Federal de Santa MariaBRQuímicaUFSMPrograma de Pós-Graduação em Química, 2013-12-03)
This work describes firstly an efficient and regioselective method for the synthesis of a new series of 2,2,2-trifluoro-1-[4-methoxy-spiro(2H-chromen-2,1 -cycloalkan)-3-yl]ethanones from the Kabbe adducts (spiro[chroman-2,1 ...
Non-covalent Carbonyl-directed Heck-matsuda Desymmetrizations: Synthesis Of Cyclopentene-fused Spirooxindoles, Spirolactones, And Spirolactams
(Wiley-V C H Verlag GmbhWeinhem, 2017)
Síntese estereosseletiva de tioespiro[4.n]alcanonas e reatividade de (E)-1-(3-benzilideno-2-metoxiciclohexenil)-2,2,2- trifluoretanona
(Universidade Federal de Santa MariaBrasilQuímicaUFSMPrograma de Pós-Graduação em QuímicaCentro de Ciências Naturais e Exatas, 2022-05-06)
The present thesis initially describes a methodology for obtaining two series of
diastereoisomers of 1-aryl-4-hydroxy-2-thiaspiro[4,5]alkan-6-ones (5a-k and 6a-k), totaling 22
novel compounds by sulfa-Michael addition ...
In vitro antiproliferative activity of 3 H-spiro [1-benzofuran-2,1'-cyclohexane] derivatives Actividad antiproliferativa in vitro de derivados de 3 H-spiro [1-benzofuran-2,1'-cyclohexano]
(2011)
The in vitro effect of the resinous exudate of Heliotropium filifolium, of the 3 H-spiro[1-benzofuran-2,1'-cyclohexane] derivative called filifolinol 1, isolated from the resin and the semi-synthetic compounds filifolinone ...
Design, facile synthesis, and evaluation of novel spiro- and pyrazolo [1,5-c]quinazolines as cholinesterase inhibitors: Molecular docking and MM/GBSA studies
(2018)
Given the wide spectrum of biological uses of pyrazolo[l,5-c]quinazoline and spiro-quinazoline derivatives as anticancer, anti-inflammatory analgesic agents, and their therapeutic applications in neurodegenerative disorders, ...