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Neurocognitive mechanisms underlying working memory encoding and retrieval in Attention-Deficit/Hyperactivity Disorder
(Nature, 2020)
Working memory (WM) impairments in ADHD have been consistently reported along with deficits in attentional control. Yet, it is not clear which specific WM processes are affected in this condition. A deficient coupling ...
Neurotoxic lesion of anteromedial/posterior parietal cortex disrupts spatial maze memory in blind rats
(2004)
The primary visual cortex of rats is surrounded laterally (in Oc2L) and medially (in Oc2M) by several peristriate visual areas. Previous studies from our laboratory demonstrated that bilateral lesions in Oc2L result in ...
Life-long environmental enrichment counteracts spatial learning, reference and working memory deficits in middle-aged rats subjected to perinatal asphyxia
(Frontiers In Bioscience Inc, 2015-01)
Continuous environmental stimulation induced by exposure to enriched environment (EE) has yielded cognitive benefits in different models of brain injury. Perinatal asphyxia results from a lack of oxygen supply to the fetus ...
Alteration of neurotrophin and cytokine expression in lymphocytes as novel peripheral markers of spatial memory deficits induced by prenatal stress
(Pergamon-Elsevier Science Ltd, 2017-05)
Much evidence has suggested that early life adversity can have a lasting effect on behavior. The aim of this study was to explore the impact of prenatal exposure to stress on cognition in adult life and how it impacts ...
Reduced power in alpha and theta bands in ADHD children during a visuo-spatial working memory task
(2017)
Deficits in visuo-spatial working memory (VSWM) are one the most common impairments in subjects with ADHD.
VSWM is associated with amplitude modulations in theta, alpha, and gamma bands. Specifically, increases in the ...
Prenatal Exposure to Cadmium During Organogenesis Impairs Memory in Young Rats
(SAGE Publications, 2019-07)
Pregnant rats were treated with 0.3 and 0.6 mg cadmium (CdCl2)/kg injected subcutaneously on a daily basis from gestational day 7 to day 15 (organogenesis period). One control group was not injected and other received ...
Impaired spatial working memory and reduced hippocampal neuronal density in a rat model of neurocysticercosis
(Frontiers, 2023)
Neurocysticercosis (NCC) is the most common parasitic disease affecting the nervous system and is a leading cause of acquired epilepsy worldwide, as well as cognitive impairment, especially affecting memory. The aim of ...
Insulin-like growth factor-I gene therapy increases hippocampal neurogenesis, astrocyte branching and improves spatial memory in female aging rats
(Wiley Blackwell Publishing, Inc, 2016-05)
In rats, learning and memory performance decline during aging, which makes this rodent species a suitable model to evaluate therapeutic strategies of potential value for correcting age‐related cognitive deficits. Some of ...
Small lesions of the dorsal or ventral hippocampus subregions are associated with distinct impairments in working memory and reference memory retrieval, and combining them attenuates the acquisition rate of spatial reference memory
(Wiley-liss, div John Wiley & Sons Inc., 2020-09)
The importance of the hippocampus in spatial learning is well established, but the precise relative contributions by the dorsal (septal) and ventral (temporal) subregions remain unresolved. One debate revolves around the ...
Papel do processo oxidativo/inflamatório na fisiopatologia induzida por concussões recorrentes em ratos jovens
(Universidade Federal de Santa MariaBrasilBioquímicaUFSMPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica ToxicológicaCentro de Ciências Naturais e Exatas, 2022-08-05)
Concussion can be defined as a change in brain function caused by an external force. In recent years, it has received greater attention from the scientific community for its subtle effects, which can add up and worsen the ...