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A framework for quantification and physical modeling of cell mixing applied to oscillator synchronization in vertebrate somitogenesis
(Company of Biologists, 2017-08)
In development and disease, cells move as they exchange signals. One example is found in vertebrate development, during which the timing of segment formation is set by a ‘segmentation clock’, in which oscillating gene ...
Paraxis is required for somite morphogenesis and differentiation in Xenopus laevis
(Wiley-liss, Div John Wiley & Sons Inc, 2015-08)
Background: In most vertebrates, the segmentation of the paraxial mesoderm involves the formation of metameric unitscalled somites through a mesenchymal-epithelial transition. However, this process is different in Xenopus ...
Wnt-regulated dynamics of positional information in zebrafish somitogenesis
(Company Of Biologists, 2014-03)
How signaling gradients supply positional information in a field of moving cells is an unsolved question in patterning and morphogenesis. Here, we ask how a Wnt signaling gradient regulates the dynamics of a wavefront of ...
Patterning embryos with oscillations: Structure, function and dynamics of the vertebrate segmentation clock
(Company of Biologists, 2012-01)
The segmentation clock is an oscillating genetic network thought to govern the rhythmic and sequential subdivision of the elongating body axis of the vertebrate embryo into somites: the precursors of the segmented vertebral ...
Morfología, estructura interna y somitogénesis de los embriones de Hyloxalus vertebralis y Dendrobates auratus (Anura: Dendrobatidae) desde la néurula hasta la eclosión del renacuajo
(QUITO / PUCE / 2012, 2012)
En el presente estudio se describe la estructura de los embriones desde la néurula
hasta la eclosión del renacuajo, de dos especies de ranas de la familia Dendrobatidae:
Hyloxalus vertebralis y Dendrobates auratus. Estas ...
Homeotic effects, somitogenesis and the evolution of vertebral numbers in recent and fossil amniotes
(National Academy of Sciences, 2010-02)
The development of distinct regions in the amniote vertebral column results from somite formation and Hox gene expression, with the adult morphology displaying remarkable variation among lineages. Mammalian regionalization ...
Segmentation of the zebrafish axial skeleton relies on notochord sheath cells and not on the segmentation clock
(eLife Sciences Publications, 2018-04)
Segmentation of the axial skeleton in amniotes depends on the segmentation clock, which patterns the paraxial mesoderm and the sclerotome. While the segmentation clock clearly operates in teleosts, the role of the sclerotome ...
RGMa and RGMb expression pattern during chicken development suggest unexpected roles for these repulsive guidance molecules in notochord formation, somitogenesis, and myogenesis
(WILEY-BLACKWELLHOBOKEN, 2012)
Background: Repulsive guidance molecules (RGM) are high-affinity ligands for the Netrin receptor Neogenin, and they are crucial for nervous system development including neural tube closure; neuronal and neural crest cell ...
Desarrollo y somitogénesis de Engystomops guayaco (Anura: Leptodactylidae) desde el huevo fecundado hasta la eclosión del renacuajo.
(PUCE, 2015)
El presente estudio propone la descripción morfológica del desarrollo temprano desde el clivaje hasta la eclosión de los renacuajos, de Engystomops guayaco, en comparación con la tabla del desarrollo del género Engystomops ...
Análisis de la diversidad del desarrollo neural y somitogénesis tempranos en siete especies de ranas
(Quito / PUCE / 2012, 2012)
En este estudio se analizó mediante un método de emparejamiento de eventos la
presencia de heterocronías en el desarrollo temprano en siete especies de ranas. Los eventos
del desarrollo temprano que se analizaron fueron: ...