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Solid dispersions with hydrogenated castor oil increase solubility, dissolution rate and intestinal absorption of praziquantel
(2010-01-01)
The solubility behavior of drugs remains one of the most challenging aspects in formulation development. Solid Dispersion (SD) has tremendous potential for improving drug solubility. Although praziquantel (PZQ) is the first ...
Effect of 70-kDa and 148-kDa dextran hydrogels on praziquantel solubility
(2016-03-01)
Praziquantel is an anthelmintic widely used in the treatment of schistosomiasis. Although a highly permeable drug, praziquantel is poorly soluble in water, limiting its bioavailability. Improving the solubility of poorly ...
Whey proteins solubility as function of temperature and pH
(Elsevier Science BvAmsterdamHolanda, 2005)
Hydroxyapatite surface solubility and effect on cell adhesion
(Elsevier Science BvAmsterdamHolanda, 2010)
Solubility of carotenoid pigments (lycopene and astaxanthin) in supercritical carbon dioxide
(ELSEVIER SCIENCE BV, 2006)
This contribution provides basic data for developing an extraction process for carotenoid compounds in terrestrial and marine plants with supercritical CO2 (SC-CO2). Specifically, the solubility (y(2), molar fraction) of ...
Physicochemical characterization of starch based films
(Elsevier, 2007-09)
In the present study, high amylose corn starch (HACS) based films were obtained with a low temperature method consisted on reduce gelatinization temperature by an alkaline pretreatment of starch. Effects of film composition ...
Behavior of low-solubility detergents
(1992)
The solubility behavior in water of different salts of cetyltrimethyl ammonium (CTA+), such as iodide (CTAI), thiocyanate (CTASCN), and perchlorate (CTAClO4), is reported. The order of solubilities is CTASCN > CTAI > ...
Synthesis and characterization of meloxicam eutectics with mandelic acid and saccharin for enhanced solubility
(2020-07-02)
Meloxicam (MLX) is a non-steroidal anti-inflammatory which is practically insoluble in water, requiring high concentrations to reach therapeutic levels and causing frequently gastrointestinal effects. In this way, the aim ...
Influence of ethanol and glycerol concentration over functional and structural properties of zein-oleic acid films
(2013-11-15)
This study was performed in order to determine the effect of the addition of different concentrations of glycerol and ethanol over functional and structural properties of zein-oleic acid films. Films were prepared from ...
Influence of ethanol and glycerol concentration over functional and structural properties of zein-oleic acid films
(2013-11-15)
This study was performed in order to determine the effect of the addition of different concentrations of glycerol and ethanol over functional and structural properties of zein-oleic acid films. Films were prepared from ...