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Structural changes in the epithelium of the small intestine and immune cell infiltration of enteric ganglia following acute mucosal damage and local inflammation
(SPRINGER, 2009)
An acute enteritis is commonly followed by intestinal neuromuscular dysfunction, including prolonged hyperexcitability of enteric neurons. Such motility disorders are associated with maintained increases in immune cells ...
P31-43 gliadin peptide forms oligomers and induces NLRP3 inflammasome/caspase 1-dependent mucosal damage in small intestine
(Frontiers Media S.A., 2019-01-30)
Celiac disease (CD) is a chronic enteropathy elicited by a Th1 response to gluten peptides in the small intestine of genetically susceptible individuals. However, it remains unclear what drives the induction of inflammatory ...
Probiotic lactobacilli as a promising strategy to ameliorate disorders associated with intestinal inflammation induced by a non-steroidal anti-inflammatory drug
(Nature Publishing Group, 2021-01-12)
Damage to the small intestine caused by non-steroidal anti-inflammatory drugs (NSAIDs) occurs more frequently than in the upper gastrointestinal tract, is more difficult to diagnose and no effective treatments exist. Hence, ...
Oral administration of probiotics increases paneth cells and intestinal antimicrobial activity
(Frontiers Media SA, 2018-04-16)
The huge amount of intestinal bacteria represents a continuing threat to the intestinal barrier. To meet this challenge, gut epithelial cells produce antimicrobial peptides (AMP) that act at the forefront of innate immunity. ...
The reactions of specific neuron types to intestinal ischemia in the guinea pig enteric nervous system
(SPRINGER, 2009)
Damage following ischemia and reperfusion (I/R) is common in the intestine and can be caused during abdominal surgery, in several disease states and following intestinal transplantation. Most studies have concentrated on ...
Pretreatment With L‐citrulline positively affects the mucosal architecture and permeability of the small intestine in a murine mucositis model
(American Society for Parenteral and Enteral Nutrition, 2018)