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Use of small interfering RNA (siRNA) as a viral replication inhibitor of Human Herpesvirus 1 in BALB/C mice with keratoconjuntivitis
(Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2018)
Modulation of the response of prostate cancer cell lines to cisplatin treatment using small interfering RNA
(2013)
Cisplatin is one of the most effective and widely used chemotherapeutic agents against several types of human cancers. However, the underlying mechanisms of action are not fully understood. We aimed to investigate the ...
Small interfering RNA for cancer treatment: overcoming hurdles in delivery
(2020)
In many ways, cancer cells are different from healthy cells. A lot of tactical nano-based drug delivery systems are based on the difference between cancer and healthy cells. Currently, nanotechnology-based delivery systems ...
Knockdown of the c-Jun-N-terminal kinase expression by siRNA inhibits MCF-7 breast carcinoma cell line growth
(2010)
We have examined the effect of two small interference RNA against Jnk-1 and Jnk-2 in the breast cancer cell line MCF-7. The expression of the JNK-1 and JNK-2 is frequently elevated in breast cancer and is a frequent genetic ...
Use of small interfering RNA (siRNA) as a viral replication inhibitor of Human Herpesvirus 1 in BALB/C mice with keratoconjuntivitis
(Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2017)
Recent advances in siRNA delivery mediated by lipid-based nanoparticles
Small interfering RNA (siRNA) has been expected to be a unique pharmaceutic for
the treatment of broad-spectrum intractable diseases. However, its unfavorable properties
such as easy degradation in the blood and ...