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Expression of SMAD proteins, TGF-beta/activin signaling mediators, in human thyroid tissues
(Sociedade Brasileira de Endocrinologia e Metabologia, 2010)
OBJECTIVE: To investigate the expression of SMAD proteins in human thyroid tissues since the inactivation of TGF-β/activin signaling components is reported in several types of cancer. Phosphorylated SMAD 2 and SMAD3 ...
Amifostine does not prevent activation of TGF beta 1 but induces smad 7 activation in megakaryocytes irradiated in vivo
(Wiley-Blackwell, 2002-11-01)
Experiments were undertaken to assess the role of amifostine in the activation of latent TGFbeta1 and in the smad proteins cascade (smad 2/3, smad4, smad7), focusing on megakaryocytes, in the bone marrow irradiated in vivo. ...
Amifostine does not prevent activation of TGF beta 1 but induces smad 7 activation in megakaryocytes irradiated in vivo
(Wiley-Blackwell, 2002-11-01)
Experiments were undertaken to assess the role of amifostine in the activation of latent TGFbeta1 and in the smad proteins cascade (smad 2/3, smad4, smad7), focusing on megakaryocytes, in the bone marrow irradiated in vivo. ...
Research Smad2 and Smad6 as predictors of overall survival in oral squamous cell carcinoma patients
(BIOMED CENTRAL LTD, 2010)
Background: To test if the expression of Smad1-8 mRNAs were predictive of survival in patients with oral squamous cell carcinoma (SCC). Patients and Methods: We analyzed, prospectively, the expression of Smad1-8, by means ...
Smad2 and Smad6 as predictors of overall survival in oral squamous cell carcinoma patients
(2010-05-12)
Abstract
Background
To test if the expression of Smad1-8 mRNAs were predictive of survival in patients with oral squamous cell carcinoma (SCC).
...
Smad2 and Smad6 as predictors of overall survival in oral squamous cell carcinoma patients
(2010-05)
Abstract
Background
To test if the expression of Smad1-8 mRNAs were predictive of survival in patients with oral squamous cell carcinoma (SCC).
Patients and Methods
We analyzed, prospectively, the ...
Smad2 and Smad6 as predictors of overall survival in oral squamous cell carcinoma patients
(2010-05-12)
Abstract
Background
To test if the expression of Smad1-8 mRNAs were predictive of survival in patients with oral squamous cell carcinoma (SCC).
...
TGF-L1 and Smad4 overexpression induce a less invasive phenotype in highly invasive spindle carcinoma cells
(Elsevier Science B.V. on behalf of the Federation of European Biochemical Societies., 2002-04-18)
We have examined the effect of transforming growth
factor L1 (TGF-L1) and overexpression of the Smad4 gene on the
phenotype of Car C, a ras mutated highly malignant spindle
carcinoma cell line. TGF-L1-treated Car C cells ...
SMAD3 is essential for transforming growth factor-β1-induced urokinase type plasminogen activator expression and migration in transformed keratinocytes
(2012)
Transforming growth factor-β1 (TGF-β1) stimulates the extracellular matrix degrading proteases expression and cell migration in order to enhance cancer cells malignancy. In the present study, we analysed the role of ...