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Correlation between charge movement and ionic current during slow inactivation in Shaker K+ channels
(ROCKEFELLER UNIV PRESS, 1997-11)
Prolonged depolarization induces a slow inactivation process in some Ki channels. We have studied ionic and gating currents during long depolarizations in the mutant Shaker H4-Delta(6-46) K+ channel and in the nonconducting ...
Pore accessibility during C-type inactivation in Shaker K+ channels
(1998)
Shaker K+ channels inactivate through two distinct molecular mechanisms: N-type, which involves the N-terminal domain and C-type that appears to involve structural modifications at the external mouth of the channel. We ...
A conducting state with properties of a slow inactivated state in a Shaker K+ channel mutant
(ROCKEFELLER UNIV PRESS, 2001-02)
In Shaker K+ channel, the amino terminus deletion Delta6-46 removes fast inactivation (N-type) unmasking a slow inactivation process. In Shaker Delta6-46 (Sh-IR) background, two additional mutations (T449V-I470C) remove ...
A new class of neurotoxin from wasp venom slows inactivation of sodium current
(Blackwell Science, 2000-06-01)
The effects of alpha-pompilidotoxin (alpha-PMTX), a new neurotoxin isolated from the venom of a solitary wasp, were studied on the neuromuscular synapses in lobster walking leg and the rat trigeminal ganglion (TG) neurons. ...
A conducting state with properties of a slow inactivated state in a shaker k+ channel mutant
(ROCKEFELLER UNIVERSITY PRESS, 2001)
A new class of neurotoxin from wasp venom slows inactivation of sodium current
(Blackwell Science, 2000-06-01)
The effects of alpha-pompilidotoxin (alpha-PMTX), a new neurotoxin isolated from the venom of a solitary wasp, were studied on the neuromuscular synapses in lobster walking leg and the rat trigeminal ganglion (TG) neurons. ...
A new class of neurotoxin from wasp venom slows inactivation of sodium current
(Blackwell Science, 2014)