Background: Leigh syndrome (LS) is a progressive neurodegenerative mitochondrial disease character-ized by necrotizing lesions affecting different parts of the central nervous system, especially in the brainstem and basal ...

Sleep is regulated by humoral and homeostatic processes. If on one hand chronic elevation of stress hormones impair sleep, on the other hand, rapid eye movement (REM) sleep deprivation induces elevation of glucocorticoids ...

The identification of biological markers that allow the early diagnosis, or even the prevention of age-related diseases, is an important goal that is being actively pursued in the research community. Sleep is one of the ...

Alternatives to positive airway pressure therapy, including surgery, represent an important area of research. Specifically, predictors of response to surgical therapy remain underdeveloped. Drug-induced sleep endoscopy ...

Objective: Rapid Eye Movement Sleep Deprivation (RSD) increases aggressiveness and is manifested in male rats as fighting episodes. The determination of the role played by such fights should constitute an important ...

Background and objective Inadequate sleep patterns may be considered a trigger to development of several metabolic diseases. Additionally, sleep deprivation and poor sleep quality can negatively impact performance in ...

Objective: to describe the total sleep time and its stages, total wake time, heart rate values and oxygen saturation shown by premature infants, and the infl uence of the periods of the day on sleep and physiological ...