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Bioadhesive Surfactant Systems for Methotrexate Skin Delivery
(2016-02-18)
Methotrexate (MTX) is an immunosuppressive drug for systemic use in the treatment of skin diseases, however, MTX presents a number of side effects, such as hepatotoxicity. To overcome this limitation, this study developed ...
Bioadhesive surfactant systems for methotrexate skin delivery
(2016-02-01)
Methotrexate (MTX) is an immunosuppressive drug for systemic use in the treatment of skin diseases, however, MTX presents a number of side effects, such as hepatotoxicity. To overcome this limitation, this study developed ...
Ascorbic acid in cosmetic formulations: Stability, in vitro release, and permeation using a rapid, inexpensive, and simple method
(Taylor & Francis Inc, 2017-01-01)
Ascorbic acid (AA) is involved in important metabolic processes in the human body. However, its chemical instability requires the assessment of products containing AA. The aim of this study was to develop systems that ...
Influence of ceramide 2 on in vitro skin permeation and retention of 5-ALA and its ester derivatives, for Photodynamic Therapy
(Universidade de São Paulo, Faculdade de Ciências Farmacêuticas, 2009)
Photodynamic therapy (PDT) based on topical 5-aminolevulinic acid (5-ALA), an endogenous precursor of protoporphyrin, is an interesting approach for the treatment of skin cancer. However, 5-ALA is a hydrophilic molecule ...
Avaliação da atividade antiproliferativa in vitro, liberação, permeação e retenção cutânea in vitro e estabilidade de emulsões contendo (-)- Terpinen-4-OL
(Universidade Estadual Paulista (Unesp), 2011-04-08)
O terpinen-4-ol é o principal componente da M. alternifólia, apresenta atividade antiinflamatória, antibacteriana e antifúngica; em estudos recentes in vitro a atividade antineoplásica para linhagens celulares de melanoma ...
Avaliação da atividade antiproliferativa in vitro, liberação, permeação e retenção cutânea in vitro e estabilidade de emulsões contendo (-)- Terpinen-4-OL
(Universidade Estadual Paulista (Unesp), 2011-04-08)
O terpinen-4-ol é o principal componente da M. alternifólia, apresenta atividade antiinflamatória, antibacteriana e antifúngica; em estudos recentes in vitro a atividade antineoplásica para linhagens celulares de melanoma ...
Avaliação da atividade antiproliferativa in vitro, liberação, permeação e retenção cutânea in vitro e estabilidade de emulsões contendo (-)- Terpinen-4-OL
(Universidade Estadual Paulista (UNESP), 2014)
In vitro studies of cutaneous retention of magnetic nanoemulsion loaded with zinc phthalocyanine for synergic use in skin cancer treatment
(ELSEVIER SCIENCE BV, 2008)
In this study was developed a new nano drug delivery system (NDDS) based on association of biodegradable surfactants with biocompatible magnetic fluid of maguemita citrate derivative. This formulation consists in a magnetic ...
Caffeic acid in dermatological formulations: In vitro release profile and skin absorption
(2017-09-01)
Aim and Objective: Caffeic acid (CA) is a cinnamic acid derivative, found in many vegetable products, with powerful antioxidant activity, the ability to increase collagen production and capacity to prevent premature aging ...
Photophysical studies and in vitro skin permeation/retention of Foscan (R)/nanoemulsion (NE) applicable to photodynamic therapy skin cancer treatment.
(AMER SCIENTIFIC PUBLISHERS, 2008)
In this work we evaluated the photophysical and in vitro properties of Foscan (R), a second-generation photosensitizer drug (PS) widely used in systemic clinical protocols for cancer therapy based on Photodynamic Therapy ...