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Schistosoma mansoni Sirtuins: Characterization and Potential as Chemotherapeutic Targets
(Public Library of Science, 2018)
Enfermedad del coronavirus(covid-19) y las sirtuinas
(Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Secretaría de Ciencia y Tecnología., 2020-06-16)
Las proteínas desacetilasas dependientes del NAD+, se denominan Sirtuinas (SIRT). Objetivos: estudiar las sirtuinas involucradas en el cáncer, así como los estudios de inhibición de SIRT1 en pacientes con la enfermedad del ...
SIRT3 deacetylase: the Jekyll and Hyde sirtuin
(Embo Press, 2011-08)
Post‐translational modifications have crucial roles in regulating the functions of many eukaryotic proteins. Among them, lysine acetylation has been traditionally studied in the context of nuclear histone modifications, ...
SIRT1 Deacetylase Activity and the Maintenance of Protein Homeostasis in Response to Stress: An Overview
(Bentham Science Publ Ltd, 2011-02-01)
The present review intends to summarize the, yet preliminary, but very important emerging data underlining the functions exerted by the nicotinamide adenine dinucleotide (NAD+)-dependent deacetylase SIRT1 on protein ...
SIRT1 Deacetylase Activity and the Maintenance of Protein Homeostasis in Response to Stress: An Overview
(Bentham Science Publ Ltd, 2011-02-01)
The present review intends to summarize the, yet preliminary, but very important emerging data underlining the functions exerted by the nicotinamide adenine dinucleotide (NAD+)-dependent deacetylase SIRT1 on protein ...
SIRT1 deacetylase activity and the maintenance of protein homeostasis in response to stress: An overview
(2011-02-01)
The present review intends to summarize the, yet preliminary, but very important emerging data underlining the functions exerted by the nicotinamide adenine dinucleotide (NAD+)-dependent deacetylase SIRT1 on protein ...
Inhibition of diethylnitrosamine-initiated alcohol-promoted hepatic inflammation and precancerous lesions by flavonoid luteolin is associated with increased sirtuin 1 activity in mice
(Hepatobiliary Surgery And Nutrition, 2015)
Chronic and excessive alcohol consumption is an established risk for hepatic inflammation and carcinogenesis. Luteolin is one of the most common flavonoids present in plants and has potential beneficial effects against ...
SIRT1 in astrocytes regulates glucose metabolism and reproductive function
(Endocrine Society, 2019-06)
Sirtuin 1 (Sirt1) is an NAD-dependent class III deacetylase that functions as a cellular energy sensor. In addition to its well-characterized effects in peripheral tissues, evidence suggests that SIRT1 in neurons plays a ...
Aggravation of nonalcoholic steatohepatitis by moderate alcohol consumption is associated with decreased SIRT1 activity in rats
(Hepatobiliary Surgery And Nutrition, 2013)
Chronic alcohol intake decreases adiponectin and sirtuin 1 (SIRT1) expressions, both of which have been implicated in various biological processes including inflammation, apoptosis and metabolism. We have previously shown ...
SIRT1 Deacetylase Activity and the Maintenance of Protein Homeostasis in Response to Stress: An Overview
(Bentham Science Publ Ltd, 2014)