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Animal Mitochondrial DNA Replication
(2016-01-01)
Recent advances in the field of mitochondrial DNA (mtDNA) replication highlight the diversity of both the mechanisms utilized and the structural and functional organization of the proteins at mtDNA replication fork, despite ...
The Essential, Ubiquitous Single-Stranded DNA-Binding Proteins
(2021-01-01)
Maintenance of genomes is fundamental for all living organisms. The diverse processes related to genome maintenance entail the management of various intermediate structures, which may be deleterious if unresolved. The most ...
Leishmania replication protein A-1 binds in vivo single-stranded telomeric DNA
(Elsevier B.V., 2007-06-29)
Replication protein A (RPA) is a highly conserved heterotrimeric single-stranded DNA-binding protein involved in different events of DNA metabolism. In yeast, subunits 1 (RPA-1) and 2 (RPA-2) work also as telomerase ...
Leishmania replication protein A-1 binds in vivo single-stranded telomeric DNA
(Elsevier B.V., 2007-06-29)
Replication protein A (RPA) is a highly conserved heterotrimeric single-stranded DNA-binding protein involved in different events of DNA metabolism. In yeast, subunits 1 (RPA-1) and 2 (RPA-2) work also as telomerase ...
Stimulation of Variant Forms of the Mitochondrial DNA Helicase Twinkle by the Mitochondrial Single-Stranded DNA-Binding Protein
(2021-01-01)
Defects in mitochondrial DNA (mtDNA) maintenance may lead to disturbances in mitochondrial homeostasis and energy production in eukaryotic cells, causing diseases. During mtDNA replication, the mitochondrial single-stranded ...
The natural absence of RPA1N domain did not impair Leishmania amazonensis RPA-1 participation in DNA damage response and telomere protection.
(2013-04-01)
We have previously shown that the subunit 1 of Leishmania amazonensis RPA (LaRPA-1) alone binds the G-rich telomeric strand and is structurally different from other RPA-1. It is analogous to telomere end-binding proteins ...
Leishmania replication protein A-1 binds in vivo single-stranded telomeric DNA
(Elsevier B.V., 2014)
Leishmania replication protein A-1 binds in vivo single-stranded telomeric DNA
(Academic Press Inc Elsevier ScienceSan DiegoEUA, 2007)
A calmodulin-like protein (LCALA) is a new Leishmania amazonensis candidate for telomere end-binding protein
(2017-11-01)
Background Leishmania spp. telomeres are composed of 5′-TTAGGG-3′ repeats associated with proteins. We have previously identified LaRbp38 and LaRPA-1 as proteins that bind the G-rich telomeric strand. At that time, we had ...
Interaction of the BELL-like protein ATH1 with DNA: Role of homeodomain residue 54 in specifying the different binding properties of BELL and KNOX proteins
(De Gruyter, 2006-01)
We have studied the interaction of the BELL-like Arabidopsis homeodomain protein ATH1 with DNA. Analysis of oligonucleotides selected by the ATH1 homeodomain from a random mixture suggests that ATH1 preferentially binds ...