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Efficacy and safety of recently approved drugs for sickle cell disease: A review of clinical trials
Sickle cell disease is prevalent in several parts of the world. Most of the hospitalizations in these
patients are related to pain crisis episodes. Moreover, the levels of hemoglobin are lower in
sickle cell disease ...
Recent Insights on the Medicinal Chemistry of Sickle Cell Disease
(Bentham Science Publ Ltd, 2011-05-01)
Sickle Cell Disease (SCD) is one of the most prevalent hematological diseases in the world. SCD is a genetic disease characterized by punctual mutation that basis on the exchange of glutamic acid to valine in a beta chain ...
Recent Insights on the Medicinal Chemistry of Sickle Cell Disease
(Bentham Science Publ Ltd, 2011-05-01)
Sickle Cell Disease (SCD) is one of the most prevalent hematological diseases in the world. SCD is a genetic disease characterized by punctual mutation that basis on the exchange of glutamic acid to valine in a beta chain ...
Recent Insights on the Medicinal Chemistry of Sickle Cell Disease
(Bentham Science Publ Ltd, 2014)
Plasma levels of TGF-β1 in homeostasis of the inflammation in sickle cell disease
(2016-04-01)
Sickle cell disease (SCD) represents a chronic inflammatory condition with complications triggered by the polymerization of hemoglobin S (Hb S), resulting in a series of cellular interactions mediated by inflammatory ...
Prevalence of Enuresis and Daytime Urinary Incontinence in Children and Adolescents With Sickle Cell Disease
(2012-03)
Purpose There is a known association between sickle cell disease and enuresis. However, the cause of this association is unclear. We tested the hypothesis that children with sickle cell disease would have more symptoms of ...
Benefits of kinesiotherapy and aquatic rehabilitation on sickle cell anemia. A case report
(Funpec-editora, 2010-01-01)
The process of hemoglobin polymerization and the consequent sickling of red blood cells that occurs in patients with sickle cell disease shortens the half-life of red blood cells. It causes vaso-occlusive complications, ...
Correlation between maxillofacial radiographic features and systemic severity as sickle cell disease severity predictor
(SPRINGER HEIDELBERGHEIDELBERG, 2013-08-02)
This study was conducted to investigate the relationship among radiographic features observed on panoramic radiographs of sickle cell disease patients and analyze their relationship with history of systemic severity of the ...
Advances in sickle cell disease treatments
(2021-01-01)
Sickle Cell Disease (SCD) is an inherited disorder of red blood cells that is caused by a single mutation in the β-globin gene. The disease, which afflicts millions of patients worldwide mainly in low income countries, is ...