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Alterações bioquímicas e estresse oxidativo associados ao hipotireoidismo
(Universidade Federal de Santa MariaBRFarmacologiaUFSMPrograma de Pós-Graduação em Farmacologia, 2010-03-18)
Overt hypothyroidism is characterized by decreased of thyroid hormones synthesis,
with elevation of thyroid-stimulating hormone (TSH). It s a common disorder in
population with highest prevalence in women and with aging. ...
Atividade das ectonucleotidases, colinesterase sérica e perfil oxidativo no diabetes melito tipo 2 e hipertensão em humanos
(Universidade Federal de Santa MariaBRBioquímicaUFSMPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica Toxicológica, 2008-03-05)
The increase in the NTPDase and 5'-nucleotidase enzymatic activities, in patients with diabetes and hypertension, unchained the investigation of the possible mechanisms involved in the alterations in ectonucleotidases ...
Human serum albumin nanoparticles for ocular delivery of bevacizumab
(Elsevier Science, 2018-04)
Bevacizumab-loaded nanoparticles (B-NP) were prepared by a desolvation process followed by freeze-drying, without any chemical, physical or enzymatic cross-linkage. Compared with typical HSA nanoparticles cross-linked with ...
Alteration of sphingolipids in biofluids: Implications for neurodegenerative Diseases
(Multidisciplinary Digital Publishing Institute, 2019-07-21)
Sphingolipids (SL) modulate several cellular processes including cell death, proliferation and autophagy. The conversion of sphingomyelin (SM) to ceramide and the balance between ceramide and sphingosine-1-phosphate (S1P), ...