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O papel das células de Sertoli na espermatogênese
(2010)
The Sertoli cell is an example of cell with specializations structural that carry out several functions simultaneously. They associate at the same time with at least four different types of germinatives cells, propitiating ...
Regulatory and junctional proteins of the blood-testis barrier in human Sertoli cells are modified by monobutyl phthalate (MBP) and bisphenol A (BPA) exposure
(2016-08-01)
The blood-testis barrier (BTB) is responsible for providing a protected environment and coordinating the spermatogenesis. Endocrine disruptors (EDs) might lead to infertility, interfering in the BTB structure and modulation. ...
In vitro effects of glyphosate and Roundup on Sertoli cell physiology
(Pergamon-Elsevier Science Ltd, 2020-02)
Roundup (R), a formulation that contains glyphosate (G) as the active ingredient, is a commonly used nonselective herbicide that has been proposed to affect male fertility. It is well known that an adequate Sertoli cell ...
Aspectos morfofuncionais das células de Sertoli de peixes teleósteos
(Universidade Estadual Paulista (Unesp), 2002-04-12)
The literature was reviewed around the Sertoli cells in teleost fish, regarding their morphological and functional aspects, importance, terminology and interaction with other testis cells. In the 76 reports searched, it ...
Selective Ablation of the Androgen Receptor in Mouse Sertoli Cells Affects Sertoli Cell Maturation, Barrier Formation and Cytoskeletal Development
(Public Library Science, 2010-11-30)
The observation that mice with a selective ablation of the androgen receptor (AR) in Sertoli cells (SC) (SCARKO mice) display a complete block in meiosis supports the contention that SC play a pivotal role in the control ...
IL17A impairs blood-testis barrier integrity and induces testicular inflammation
(Springer, 2014-09)
Experimental autoimmune orchitis is a useful model for studying testicular inflammation and germ/immune cell interactions. Th17 cells and their hallmark cytokine IL17A were reported to be involved in the development of ...
Molecular mechanisms and signaling pathways involved in Sertoli cell proliferation
(Frontiers Media, 2019-04)
Sertoli cells are somatic cells present in seminiferous tubules which have essential roles in regulating spermatogenesis. Considering that each Sertoli cell is able to support a limited number of germ cells, the final ...
Modulação de proteínas regulatórias e juncionais da barreira hematotesticular em células de Sertoli humanas (HSec) expostas ao Monobutil ftalato (MBP) e ao Bisfenl A (BPA)
(Universidade Estadual Paulista (Unesp), 2015-02-25)
Sertoli cells, found in the seminiferous epithelium, form the blood-testis barrier via their gap and tight junctions, responsible for providing a protected environment and coordinate the spermatogenic process, essential ...