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De-escalation of antimicrobial treatment for adults with sepsis, severe sepsis or septic shock
(Wiley-Blackwell, 2013-01-01)
BackgroundMortality rates among patients with sepsis, severe sepsis or septic shock are highly variable throughout different regions or services and can be upwards of 50%. Empirical broad-spectrum antimicrobial treatment ...
Management of septic shock with a norepinephrine-based haemodynamic algorithm
(ELSEVIER IRELAND LTD, 2005)
Management of septic shock (SS) with a norepinephrine (noradrenaline)-based haemodynamic algorithm. Introduction: The choice of the best vasopressor for haemodynamic management of septic shock is controversial. Nevertheless, ...
Insights Into Thiamine Supplementation in Patients With Septic Shock
(2022-01-28)
Septic shock is associated with unacceptably high mortality rates, mainly in developing countries. New adjunctive therapies have been explored to reduce global mortality related to sepsis. Considering that metabolic changes, ...
Septic arthritis as the first sign of Candida tropicalis fungaemia in an acute lymphoid leukemia patient
(Brazilian Society of Infectious Diseases, 2003-12-01)
Fungal infections caused by Candida species have increased in incidence during the past two decades in England, North America and Europe. Candidal arthritis is rare in patients who are not intravenous drug users or are who ...
Ação dos inotrópicos e vasopressores na estabilização hemodinâmica em cães com choque séptico
(Universidade Estadual Paulista (Unesp), 2011)
Septic shock remains one of the most common challenges for the small animal practicing, presenting high mortality rates frequently associated with late identification of this syndrome, as well as an inappropriate treatment. ...
A hypoperfusion context may aid to interpret hyperlactatemia in sepsis-3 septic shock patients : a proof-of-concept study
(2017)
Abstract
Background
Persistent hyperlactatemia is particularly difficult to interpret in septic shock. Besides hypoperfusion, adrenergic-driven lactate production and ...
Current use of inotropes in circulatory shock
(2021)
Abstract
Background
Treatment decisions on critically ill patients with circulatory shock lack consensus. In an international survey, we aimed to evaluate the indications, ...
Pharmacokinetics and pharmacodynamics of antibiotics in critically ill acute kidney injury patients
(2016-12-01)
Sepsis is the most common cause of death in critically ill patients and is associated with multiorgan failure, including acute kidney injury (AKI). This situation can require acute renal support and increase mortality. ...