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Senescence-Associated Vacuoles, a Specific Lytic Compartment for Degradation of Chloroplast Proteins?
(Molecular Diversity Preservation International, 2014-11)
Degradation of chloroplasts and chloroplast components is a distinctive feature of leaf senescence. In spite of its importance in the nutrient economy of plants, knowledge about the mechanism(s) involved in the breakdown ...
Macroautophagy and the oncogene-induced senescence
(Frontiers, 2014-09)
The oncogene-induced senescence is emerging as a potent tumor suppressor mechanism and as a possible therapeutic target. Macroautophagy is intimately linked to the senescence condition setup, although its role has not been ...
Senescence-associated proteases in plants
(Wiley Blackwell Publishing, Inc, 2012-05)
Senescence is the final developmental stage of every plant organ, which leads to cell death. It is a highly regulated process, involving differential gene expression and outstanding increment in the rate of protein ...
Increased production of functional small extracellular vesicles in senescent endothelial cells
(Wiley, 2020)
Small extracellular vesicles (EVs) are novel players in vascular biology. However, a thorough understanding of their production and function remains elusive. Endothelial senescence is a key feature of vascular ageing and ...
Chloroplast protein degradation in senescing leaves: Proteases and lytic compartments
(Frontiers Media, 2019-06-19)
Leaf senescence is characterized by massive degradation of chloroplast proteins, yet the protease(s) involved is(are) not completely known. Increased expression and/or activities of serine, cysteine, aspartic, and ...
Palbociclib-Induced Cellular Senescence Is Modulated by the mTOR Complex 1 and Autophagy
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)
In vivo inhibition of cysteine proteases provides evidence for the involvement of ‘senescence-associated vacuoles’ in chloroplast protein degradation during dark-induced senescence of tobacco leaves
(Oxford University Press, 2013-07)
Breakdown of leaf proteins, particularly chloroplast proteins, is a massive process in senescing leaves. In spite of its importance in internal N recycling, the mechanism(s) and the enzymes involved are largely unknown. ...