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A comparison of the effects of the selective peripheral α1-blocker terazosin with the selective β1-blocker atenolol on blood pressure, exercise performance and the lipid profile in mild-to-moderate essential hypertension
(Springer-Verlag, 1992)
The effects of six weeks of treatment with the selective peripheral α1-adrenoceptor blocker terazosin, or the selective β1-adrenoceptor blocker atenolol on blood pressure, exercise performance and blood lipid profile were ...
Functional expression of the α7 and α4-containing nicotinic acetylcholine receptors on the neonatal rat carotid body
(2012)
The carotid bodies (CBs) are chemosensory organs that respond to hypoxemia with transmitter neurosecretion, leading to a respiratory reflex response. It has been proposed that acetylcholine is a key regulator of transmitter ...
α-RgIA: A novel conotoxin that specifically and potently blocks the α9α10 nAChR
(American Chemical Society, 2006-02)
The α9 and α10 nicotinic acetylcholine receptor (nAChR) subunits assemble to form the α9α10 nAChR subtype. This receptor is believed to mediate cholinergic synaptic transmission between efferent olivocochlear fibers and ...
Updates in the function and regulation of α1-adrenoceptors
(2019-07-01)
α1-Adrenoceptors are seven transmembrane domain GPCRs involved in numerous physiological functions controlled by the endogenous catecholamines, noradrenaline and adrenaline, and targeted by drugs useful in therapeutics. ...
Production of optically active (α)-monobenzoyl glycerol catalyzed by CALB lipase immobilized on silica octyl Support
(2013)
Optically active (α)-monobenzoate glycerol ((α)-MBG) is known to be a useful
starting compound for the preparation of chiral drugs, such as β blockers,
platelet activating factor and (S)-carnitine [1]. The reaction ...
Velhas drogas, novas terapêuticas: investigação da utilização de antagonistas de adrenoceptores α1 e de bloqueadores de canais de cálcio no retardo da ejaculação
(Universidade Estadual Paulista (Unesp), 2010-06-23)
A ejaculação precoce é a disfunção sexual masculina com maiores taxas de incidência e prevalência. De etiologia complexa, as principais abordagens farmacológicas desta condição têm sido a utilização de anestésicos locais, ...
Velhas drogas, novas terapêuticas: investigação da utilização de antagonistas de adrenoceptores α1 e de bloqueadores de canais de cálcio no retardo da ejaculação
(Universidade Estadual Paulista (Unesp), 2010-06-23)
A ejaculação precoce é a disfunção sexual masculina com maiores taxas de incidência e prevalência. De etiologia complexa, as principais abordagens farmacológicas desta condição têm sido a utilização de anestésicos locais, ...
Velhas drogas, novas terapêuticas: investigação da utilização de antagonistas de adrenoceptores α1 e de bloqueadores de canais de cálcio no retardo da ejaculação
(Universidade Estadual Paulista (UNESP), 2014)
Mifepristone, a blocker of glucocorticoid receptors, promotes photoreceptor death
(Association for Research in Vision and Ophthalmology, 2013-01)
PURPOSE: Glucocorticoids are best known by their protective effect on retinal photoreceptor damage. However, they could also be involved in photoreceptor homeostasis under basal, nonstressful conditions. Therefore, we aimed ...