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Heterogeneity in composition of mouse uterine natural killer cell granules
(Federation Amer Soc Exp BiolBethesdaEUA, 2012)
The mammalian acrosome as a secretory lysosome: new and old evidence
(WILEY-LISS, 2006)
Neuronopathic Gaucher disease: Beyond lysosomal dysfunction
(2022)
Gaucher disease (GD) is an inherited disorder caused by recessive mutations in the GBA1 gene that encodes the lysosomal enzyme beta-glucocerebrosidase (beta-GC). beta-GC hydrolyzes glucosylceramide (GluCer) into glucose ...
Targeting exogenous β-defensin to the endolysosomal compartment via a vehicle guided system
(Francisco Hernandez, 2017-10)
A number of pathogens for which there are no effective treatments infect the cells via endocytosis. Once in the endosomes, the pathogens complete their life cycle by overriding normal lysosomal functions. Recently, our ...
Phospholipase D2:A Pivotal Player Modulating RBL-2H3 Mast Cell Structure
(SAGE PUBLICATIONS LTDLONDON, 2012)
The current study examined the role of PLD2 in the maintenance of mast cell structure. Phospholipase D (PLD) catalyzes hydrolysis of phosphatidylcholine to produce choline and phosphatidic acid (PA). PLD has two isoforms, ...
Glucosidase II and MRH-Domain Containing Proteins in the Secretory Pathway
(Bentham Science Publishers, 2015-01)
N-glycosylation in the endoplasmic reticulum (ER) consists of the transfer of a preassembled glycan conserved among species (Glc3Man9GlcNAc2) from a lipid donor to a consensus sequence within a nascent protein that is ...