Malignant hypertension is a well-defined condition associated with high blood pressure and acute target-organ damage. Although 95% of cases are secondary to essential hypertension, its etiological profile is broad. ...

We report the case of a 44 year-old female, who presented a long-lasting, clinically atypical, secondary syphilis (malignant syphilis) in the right foot, which started six months before medical evaluation. The patient had ...

Thrombotic microangiopathy (TMA) is a condition characterized by thrombocytopenia and microangiopathic hemolytic anemia (MAHA) with varying degrees of organ damage in the setting of normal International Normalized Ratio ...

Introduction: Malignant priapism or priapism secondary to metastatic infiltration is rarely seen condition. Most patients present with extensive involvement of the primary disease, and with few options for medical or ...

Early malignant syphilis is a rare and severe variant of secondary syphilis. It is clinically characterized by lesions, which can suppurate and be accompanied by systemic symptoms such as high fever, asthenia, myalgia, and ...

Herein, we describe a 25-year-old man who presented a rare widespread form of secondary syphilis characterized by fever and disseminated ulcerative crusted lesions of 1 month duration and in whom malignant syphilis was ...

CONTEXT: Primary malignancy in giant cell tumor (PMGCT) is rare. It is defined as a high-grade sarcoma originating in a giant cell tumor (GCT) and seems to behave less aggressively than its secondary counterpart does. CASE ...

In this review, we discuss disease-causing alterations of RUNT-related transcription factor 1 (RUNX1), a master regulator of hematopoietic differentiation. Familial platelet disorder with predisposition to myeloid leukemia ...